Pla2g15 - phospholipase A2, group XV Gene

Also Known as ACS; LLPL; LPLA2; Lypla3; 1-O-acylceramidesynthase

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 361401

Summary

Enables O-acyltransferase activity and calcium-independent Phospholipase A2 activity. Involved in ceramide metabolic process and phosphatidylcholine metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in extracellular space and lysosome. Orthologous to human PLA2G15 (Phospholipase A2 group XV). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g15 Products (1)

mRNA Protein Name
NM_001004277.2 NP_001004277.1 phospholipase A2 group XV precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables O-acyltransferase activity IDA
IDA: Inferred from direct assay
15294901 RGD
enables calcium-independent phospholipase A2 activity IDA
IDA: Inferred from direct assay
15294901 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in ceramide metabolic process IDA
IDA: Inferred from direct assay
15294901 RGD
involved in phosphatidylcholine metabolic process IMP
IMP: Inferred from mutant phenotype
11238016 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipase A2 group XV

  • 1-O-acylceramide synthase

  • LCAT-like lysophospholipase

  • group XV phospholipase A2

  • lysophospholipase 3

  • lysosomal phospholipase A and acyltransferase

  • lysosomal phospholipase A2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-18542 KT195 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS10619 PLA2G15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17862 Pla2g15 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24331 Pla2g15 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Pla2g15 NCBI NCBI:23659