Postn - periostin Gene

Also Known as Plf

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361945

Summary

Predicted to enable cell adhesion molecule binding activity; heparin binding activity; and metal ion binding activity. Involved in several processes, including bone regeneration; cellular response to growth factor stimulus; and negative regulation of cell-substrate adhesion. Located in cytoplasm; extracellular space; and neuromuscular junction. Used to study congestive heart failure. Biomarker of artery disease (multiple); degenerative disc disease; end stage renal disease; periodontitis; and tendinitis. Orthologous to human POSTN (periostin). [provided by Alliance of Genome Resources, Apr 2022]

Postn Products (1)

mRNA Protein Name
NM_001108550.1 NP_001102020.1 periostin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19478074 RGD
Biological Process GO Annotation Evidence References Source
involved in bone regeneration IEP
IEP: Inferred from expression pattern
17878602 RGD
involved in cellular response to fibroblast growth factor stimulus IEP
IEP: Inferred from expression pattern
16325820 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: Inferred from expression pattern
22886209 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
20458732 RGD
involved in negative regulation of cell-matrix adhesion IDA
IDA: Inferred from direct assay
15381649 RGD
involved in negative regulation of substrate adhesion-dependent cell spreading IDA
IDA: Inferred from direct assay
15381649 RGD
involved in neuron projection extension IMP
IMP: Inferred from mutant phenotype
24523534 RGD
involved in positive regulation of chemokine (C-X-C motif) ligand 2 production IMP
IMP: Inferred from mutant phenotype
24260297 RGD
involved in positive regulation of smooth muscle cell migration IMP
IMP: Inferred from mutant phenotype
16325820 RGD
involved in regulation of systemic arterial blood pressure IDA
IDA: Inferred from direct assay
15381649 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
18270434 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
15121739 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
23453657 RGD
involved in response to muscle activity IEP
IEP: Inferred from expression pattern
19620321 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
19006175 RGD
located in neuromuscular junction IDA
IDA: Inferred from direct assay
19620321 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

periostin

  • periostin, osteoblast specific factor

  • periostin-like factor

Recombinant Postn Proteins

Cat. No. Product Name Accession Purity
HY-P79348 Periostin/OSF-2 Protein, Rat (HEK293, His) D3ZAF5 (N24-S800) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10884 POSTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16974 Postn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23417 Postn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Postn NCBI NCBI:10631