Tnfrsf10b - TNF receptor superfamily member 10b Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364420

Summary

Predicted to enable identical protein binding activity and protease binding activity. Involved in extrinsic apoptotic signaling pathway via death domain receptors; male gonad development; and response to organic cyclic compound. Located in membrane. Biomarker of colon Cancer and osteoarthritis. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic Cancer (multiple); and urinary bladder Cancer. Orthologous to human TNFRSF10A (TNF Receptor Superfamily member 10a). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf10b Products (1)

mRNA Protein Name
NM_001395720.1 NP_001382649.1 TNF receptor superfamily member 10b precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in extrinsic apoptotic signaling pathway via death domain receptors IMP
IMP: Inferred from mutant phenotype
19934367 RGD
involved in male gonad development IEP
IEP: Inferred from expression pattern
12021051 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TNF receptor superfamily member 10b

  • tumor necrosis factor receptor superfamily, member 10b

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99260 Conatumumab Agonist 98.90% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181955 MS1129 / Unkown
HY-RS14796 TNFRSF10B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17570 Tnfrsf10b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24030 Tnfrsf10b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf10b NCBI NCBI:8795