WEE1 - WEE1 G2 checkpoint kinase Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 476847

About WEE1

Primary_assembly 21: 33,722,005-33,737,604 forward strand.ROS_Cfam_1.0:CM025120.1

This gene has 2 transcripts (splice variants), 227 orthologues and 7 paralogues.

WEE1 Products (3)

mRNA Protein Name
XM_038430485.1 XP_038286413.1 wee1-like protein kinase isoform X3
XM_038430483.1 XP_038286411.1 wee1-like protein kinase isoform X1
XM_038430484.1 XP_038286412.1 wee1-like protein kinase isoform X2

WEE1 Protein Structure

PHA03307

PHA03307: cl33723 (48 - 168)

PTKc_Wee1a

PTKc_Wee1a: cd14138 (293 - 568)

  • 0
  • 200
  • 400
  • 600
  • 665 a.a.
Protein Preferred Names Protein Names

wee1-like protein kinase

  • WEE1 homolog

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-10993 Adavosertib Inhibitor 99.96% Phase 2
HY-145817A lunresertib Inhibitor 99.97% Phase 2
HY-182906 XL495 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (70)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-132295 Azenosertib Inhibitor 99.96% Unkown
HY-13925 PD0166285 Inhibitor 99.46% Unkown
HY-147054 Zedoresertib Inhibitor 99.85% Unkown
HY-175749 BMS-986463 Degrader 98.63% Unkown
HY-N0819 Raddeanin A Inhibitor 98.68% Unkown
HY-18961 PD 407824 Inhibitor 99.00% Unkown
HY-122113 PD173952 Inhibitor 99.58% Unkown
HY-W1135319 SB-405483 99.33% Unkown
HY-133618 Pomalidomide-C3-adavosertib Degrader 99.84% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-147312 GSK-1520489A Inhibitor 99.83% Unkown
HY-108343 WEE1-IN-4 Inhibitor 99.70% Unkown
HY-103029 Bosutinib isomer Inhibitor 99.62% Unkown
HY-148062 RSS0680 98.03% Unkown
HY-145817 (Rac)-lunresertib Inhibitor 99.72% Unkown
HY-170517 PKMYT1-IN-8 Inhibitor 99.31% Unkown
HY-173320 HEMTAC WEE1 degrader-1 Degrader 99.78% Unkown
HY-144999 LEB-03-146 98.08% Unkown
HY-138239 WEE1-IN-3 Inhibitor 98.64% Unkown
HY-168654 WEE1 degrader 1 Degrader 99.74% Unkown
HY-145664 Myt1-IN-1 Inhibitor 98.97% Unkown
HY-161880 WEE1-IN-10 Inhibitor / Unkown
HY-163697 WEE1-IN-7 Inhibitor 99.70% Unkown
HY-145666 Myt1-IN-3 Inhibitor 99.14% Unkown
HY-W070306 PDK1-IN-1 Inhibitor 99.95% Unkown
HY-169946 WEE1/PKMYT1-IN-1 Inhibitor 98.84% Unkown
HY-163490 PKMYT1-IN-1 Inhibitor 99.24% Unkown
HY-145817B (R)-lunresertib Inhibitor 99.87% Unkown
HY-180485 PROTAC D16-M1P2 Degrader / Unkown
HY-145665 Myt1-IN-2 Inhibitor / Unkown
HY-178190 WEE1-IN-13 Inhibitor / Unkown
HY-163491 PKMYT1-IN-2 Inhibitor / Unkown
HY-169946B WEE1/PKMYT1-IN-3 Inhibitor / Unkown
HY-178150 WEE1-IN-14 Inhibitor / Unkown
HY-133703A i-AZD1775 TFA Inhibitor / Unkown
HY-13925A PD0166285 dihydrochloride Inhibitor / Unkown
HY-182791 BAA-009 Inhibitor / Unkown
HY-176957 PKMYT1-IN-11 Inhibitor / Unkown
HY-143342 LEB-03-144 / Unkown
HY-183278 APO-50815 Inhibitor / Unkown
HY-175817 PKMYT1-IN-10 Inhibitor / Unkown
HY-157443 Myt1-IN-4 Inhibitor / Unkown
HY-183547 WEE1/PKMYT1-IN-4 Inhibitor / Unkown
HY-176283 Tubulin/LSD1-IN-1 Inhibitor / Unkown
HY-179272 Wee1/HDAC-IN-1 Inhibitor / Unkown
HY-160530 WEE1-IN-6 Inhibitor / Unkown
HY-143340 LEB-03-145 / Unkown
HY-160948 DB07006 Inhibitor / Unkown
HY-172759 PKMYT1-IN-9 Inhibitor / Unkown
HY-180484 PKMYT1-IN-12 Inhibitor / Unkown
HY-174448 WEE1-IN-12 Inhibitor / Unkown
HY-143343 LEB-03-153 / Unkown
HY-162849 PKMYT1-IN-3 Inhibitor / Unkown
HY-172807 p38α-IN-9 Inhibitor / Unkown
HY-176363 Adavosertib-C3-NH-Boc Inhibitor / Unkown
HY-168180 WEE1-IN-11 Inhibitor / Unkown
HY-180893 XH-30 Inhibitor / Unkown
HY-169946A WEE1/PKMYT1-IN-2 Inhibitor / Unkown
HY-175261 DHI1 Inhibitor / Unkown
HY-182790 BAA-065 Inhibitor / Unkown
HY-175819 PD-166285 Inhibitor / Unkown
HY-161871 WEE1-IN-8 Inhibitor / Unkown
HY-182433 CJM061 Inhibitor / Unkown
HY-161879 WEE1-IN-9 Inhibitor / Unkown
HY-159937 PKMYT1-IN-7 Inhibitor / Unkown
HY-162986 PKMYT1-IN-4 Inhibitor / Unkown
HY-162988 Myt1-IN-5 Inhibitor / Unkown
HY-N0819R Raddeanin A (Standard) / Unkown
HY-162987 PKMYT1-IN-6 Inhibitor / Unkown
HY-176853 Myt1-IN-6 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens WEE1 NCBI NCBI:7465