Spib - Spi-B transcription factor Gene

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in immature B cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within macrophage differentiation and regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human SPIB (Spi-B transcription factor). [provided by Alliance of Genome Resources, Apr 2022]