Izumo1 - izumo sperm-oocyte fusion 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 499152

Summary

Enables protein homodimerization activity. Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization; heterotypic cell-cell adhesion; and sperm-egg recognition. Predicted to be located in acrosomal vesicle. Predicted to be active in acrosomal membrane and plasma membrane. Predicted to be integral component of membrane. Orthologous to human IZUMO1 (izumo sperm-egg fusion 1). [provided by Alliance of Genome Resources, Apr 2022]

Izumo1 Products (1)

mRNA Protein Name
NM_001017514.1 NP_001017514.1 izumo sperm-egg fusion protein 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
19658160 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

izumo sperm-egg fusion protein 1

  • OBF

  • izumo sperm-egg fusion 1

  • oocyte binding/fusion factor

  • sperm-specific protein izumo

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07004 IZUMO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07005 IZUMO1R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19263 Izumo1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21242 Izumo1r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25752 Izumo1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27759 Izumo1r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Izumo1 NCBI NCBI:284359