APC - APC regulator of WNT signaling pathway Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 533233

About APC

Primary_assembly 10: 1,167,671-1,299,249 reverse strand.ARS-UCD1.2:CM008177.2

This gene has 6 transcripts (splice variants), 169 orthologues and 1 paralogue.

APC Products (1)

mRNA Protein Name
NM_001075986.2 NP_001069454.2 adenomatous polyposis coli protein

APC Protein Structure

Suppressor_APC

Suppressor_APC: pfam11414 (136 - 216)

SMC_prok_A

SMC_prok_A: cl37070 (143 - 331)

ARM

ARM: smart00185 (382 - 434)

APC_rep

APC_rep: pfam18797 (435 - 508)

ARM

ARM: sd00043 (532 - 568)

ARM

ARM: smart00185 (572 - 613)

ARM

ARM: sd00043 (576 - 613)

ARM

ARM: sd00043 (623 - 655)

ARM

ARM: sd00043 (663 - 704)

ARM

ARM: smart00185 (709 - 749)

ARM

ARM: sd00043 (713 - 747)

Arm

Arm: pfam00514 (751 - 791)

ARM

ARM: sd00043 (755 - 791)

Arm_APC_u3

Arm_APC_u3: pfam16629 (792 - 1079)

APC_u5

APC_u5: pfam16630 (1096 - 1195)

APC_r

APC_r: pfam05923 (1319 - 1336)

APC_u9

APC_u9: pfam16633 (1345 - 1430)

APC_r

APC_r: pfam05923 (1433 - 1455)

APC_r

APC_r: pfam05923 (1703 - 1726)

APC_u13

APC_u13: pfam16634 (1728 - 1781)

SAMP

SAMP: pfam05924 (1782 - 1803)

APC_u14

APC_u14: pfam16635 (1812 - 1905)

APC_u15

APC_u15: pfam16636 (1939 - 2013)

SAMP

SAMP: pfam05924 (2100 - 2119)

APC_basic

APC_basic: pfam05956 (2290 - 2635)

EB1_binding

EB1_binding: pfam05937 (2737 - 2911)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2912 a.a.
Protein Preferred Names Protein Names

adenomatous polyposis coli protein

  • APC, WNT signaling pathway regulator

  • adenomatosis polyposis coli

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112968 Human protein C / Unkown

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124955 proTAME Inhibitor 98.20% Unkown
HY-110287 Apcin Inhibitor 99.62% Unkown
HY-13255 TAME Inhibitor 99.51% Unkown
HY-130841 Apcin-A Inhibitor 98.0% Unkown
HY-P1918 Activated Protein C (390-404), human 98.74% Unkown
HY-13255A TAME hydrochloride Inhibitor 98.31% Unkown
HY-122142A Pyr-​Pro-​Arg-​pNA (hydrochloride) Substrate 99.24% Unkown
HY-182052 Ferroptosis inducer-16 Inhibitor / Unkown
HY-112968A Bovine Protein C / Unkown
HY-122142 Pyr-​Pro-​Arg-​pNA Substrate / Unkown
HY-126016 MAI-400 Inhibitor / Unkown
HY-P1918A Activated Protein C (390-404), human TFA / Unkown
HY-116473 CFM-1 Antagonist / Unkown
HY-179012 CDC20/HSP90-IN-1 Inhibitor / Unkown
HY-172401 CDC20-IN-2 Inhibitor / Unkown
HY-W614725 Apcin-A monohydrochloride Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992193 Anti-B7-H7 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens APC NCBI NCBI:324