ELP6 - elongator acetyltransferase complex subunit 6 Gene

Also Known as C3orf75; TMEM103

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54859

About ELP6

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:47,495,640-47,513,712 (from NCBI)

This gene has 15 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in testis (RPKM 3.4), adrenal (RPKM 3.4) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of cell migration. Located in cytosol and nucleus. Part of elongator holoenzyme complex. [provided by Alliance of Genome Resources, Apr 2022]

ELP6 Products (2)

mRNA Protein Name
NM_001031703.3 NP_001026873.2 elongator complex protein 6 isoform 1
NM_001363957.1 NP_001350886.1 elongator complex protein 6 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22854966 GOA
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
22645656 GOA
part of elongator holoenzyme complex IDA
IDA: Inferred from direct assay
22854966 GOA
part of elongator holoenzyme complex IPI
IPI: Inferred from physical interaction
22854966 GOA
located in nucleus IDA
IDA: Inferred from direct assay
22645656 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELP6 Protein Structure

ELP6

ELP6: Elongation complex protein 6 (1 - 251)

  • 0
  • 100
  • 200
  • 266 a.a.
Protein Preferred Names Protein Names

elongator complex protein 6

  • UPF0405 protein C3orf75

ELP6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ELP6 Q0PNE2 ELP5 Homo sapiens Q8TE02
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Lipid Pneumonia

  • Exogenous Lipoid Pneumonia

  • Lipoid Pneumonitis

  • Pneumonia, Lipid

  • Pneumonia Lipid

  • Lipoid Pneumonia
Neuropathy, Hereditary Sensory And Autonomic, Type Iii

  • Familial Dysautonomia

  • Riley-Day Syndrome

  • Dysautonomia, Familial

  • HSAN3

  • Hsan Iii

  • Fd

  • Hereditary Sensory And Autonomic Neuropathy Type Iii

  • Dys

  • Hereditary Sensory And Autonomic Neuropathy 3

  • Riley Day Syndrome

  • Familial Autonomic Nervous Dysfunction

  • Hereditary Sensory Autonomic Neuropathy Type Iii

  • Hsan 3

  • Hsn 3

  • Hereditary Sensory Neuropathy Type 3

  • Hsan Type Iii

  • Hsn-Iii

  • Hereditary Sensory And Autonomic Neuropathy Type 3

  • Neuropathy, Hereditary Sensory And Autonomic, 3

  • Hsn Iii

  • Dysautonomia Familial

  • Neuropathy, Sensory And Autonomic, Hereditary, Type Iii

  • Hsan3 - [Hereditary Sensory And Autonomic Neuropathy Type 3]
Vasomotor Rhinitis

  • Rhinitis, Vasomotor

  • Rhinitis Vasomotor

  • Vmr - [Vasomotor Rhinitis]
Hereditary Sensory Neuropathy

  • Hereditary Sensory And Autonomic Neuropathy

  • Hereditary Sensory And Autonomic Neuropathies

  • Familial Dysautonomia, Type Ii

  • Hsan

  • Sensory Neuropathy Hereditary

  • Neuropathy, Sensory And Autonomic, Hereditary

  • Neuropathy, Sensory, Hereditary

  • Sensory Neuropathy, Hereditary

  • Charcot-Marie-Tooth Disease

  • Cmt - [Charcot-Marie-Tooth Disease]
Benign Epilepsy With Centrotemporal Spikes

  • Rolandic Epilepsy

  • Benign Rolandic Epilepsy

  • Epilepsy, Rolandic

  • Bcects

  • Benign Childhood Epilepsy With Centrotemporal Spike

  • Sylvan Seizures

  • Becrs

  • Bects

  • Bre

  • Benign Epilepsy Of Childhood With Centrotemporal Spikes

  • Benign Familial Epilepsy Of Childhood With Rolandic Spikes

  • Centrotemporal Epilepsy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04333 ELP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20727 Elp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27239 Elp6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ELP6 MGD MGI:1919349
Bos taurus ELP6 VGNC VGNC:28459
Felis catus ELP6 VGNC VGNC:61830
Rattus norvegicus ELP6 RGD RGD:1305478
Macaca mulatta ELP6 VGNC VGNC:72113
Canis familiaris ELP6 VGNC VGNC:49826
Others ELP6 NCBI