SAGE1 - sarcoma antigen 1 Gene

Homo sapiens

Also known as CT14; SAGE

Gene ID: 55511 | Gene type: protein coding

About SAGE1

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:135,893,716-135,913,062 (from NCBI)

This gene has 2 transcripts (splice variants), 52 orthologues and 11 paralogues. Restricted expression toward testis (RPKM 2.8).

Summary

This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for Cancer Immunotherapy. This gene is expressed in sarcomas. [provided by RefSeq, Jul 2008]

SAGE1 Products(2)

mRNA	Protein	Name
NM_001381902.1	NP_001368831.1	sarcoma antigen 1
NM_018666.3	NP_061136.2	sarcoma antigen 1

SAGE1 Protein Structure

INT_SG_DDX_CT_C

0
200
400
600
800
904 a.a.

Protein Preferred Names

Protein Names

sarcoma antigen 1

cancer/testis antigen 14

Related Diseases

Diseases

Alias

Chronic Inflammation Of Lacrimal Passage

Dacryocystocele

Lacrimal Mucocele

Clivus Meningioma

Meningioma Of The Clivus

Sarcoma

Connective And Soft Tissue Neoplasm	Tumor Of Soft Tissue And Skeleton
Sarcomas	Sarcoma - Category

Retroperitoneal Fibrosis

Idiopathic Retroperitoneal Fibrosis	Ormond Disease
Igg4-Related Retroperitoneal Fibrosis	Ormond'S Disease
Rpf - [Retroperitoneal Fibrosis]

Orange Allergy

Citrus Sinensis Fruit Allergy

Acute Vascular Insufficiency Of Intestine

Acute Gastrointestinal Tract Vascular Insuffic.	Acute Git Vascular Insuffic.
Acute Intestinal Ischemia	Acute Intestinal Vascular Insufficiency

Spermatocytoma

Spermatocytic Seminoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12416	SAGE1 Human Pre-designed siRNA Set A		/	Unkown

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