SAGE1 - sarcoma antigen 1 Gene

Also Known as CT14; SAGE

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55511

About SAGE1

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:135,893,716-135,913,062 (from NCBI)

This gene has 2 transcripts (splice variants), 52 orthologues and 11 paralogues. Restricted expression toward testis (RPKM 2.8).

Summary

This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for Cancer Immunotherapy. This gene is expressed in sarcomas. [provided by RefSeq, Jul 2008]

SAGE1 Products (2)

mRNA Protein Name
NM_001381902.1 NP_001368831.1 sarcoma antigen 1
NM_018666.3 NP_061136.2 sarcoma antigen 1

SAGE1 Protein Structure

INT_SG_DDX_CT_C

INT_SG_DDX_CT_C: INTS6/SAGE1/DDX26B/CT45 C-terminus (821 - 884)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 904 a.a.
Protein Preferred Names Protein Names

sarcoma antigen 1

  • cancer/testis antigen 14

SAGE1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P81405 SAGE1 Antibody (YA1150) IHC-P Human
HY-P81405A SAGE1 Antibody (YA1150)(PBS only) IHC-P Human

Related Diseases

Diseases Alias
Chronic Inflammation Of Lacrimal Passage
Dacryocystocele
  • Lacrimal Mucocele

Clivus Meningioma
  • Meningioma Of The Clivus

Sarcoma
  • Connective And Soft Tissue Neoplasm

  • Tumor Of Soft Tissue And Skeleton

  • Sarcomas

  • Sarcoma - Category

Retroperitoneal Fibrosis
  • Idiopathic Retroperitoneal Fibrosis

  • Ormond Disease

  • Igg4-Related Retroperitoneal Fibrosis

  • Ormond'S Disease

  • Rpf - [Retroperitoneal Fibrosis]

Orange Allergy
  • Citrus Sinensis Fruit Allergy

Acute Vascular Insufficiency Of Intestine
  • Acute Gastrointestinal Tract Vascular Insuffic.

  • Acute Git Vascular Insuffic.

  • Acute Intestinal Ischemia

  • Acute Intestinal Vascular Insufficiency

Spermatocytoma
  • Spermatocytic Seminoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma