NLN - neurolysin Gene

Also Known as MEP; MOP; AGTBP; EP24.16

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57486

About NLN

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,722,205-65,829,283 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in liver (RPKM 3.9), brain (RPKM 3.5) and 25 other tissues.

Summary

This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010]

NLN Products (1)

mRNA Protein Name
NM_020726.5 NP_065777.1 neurolysin, mitochondrial

NLN Protein Structure

Peptidase_M3

Peptidase_M3: Peptidase family M3 (251 - 700)

  • 0
  • 200
  • 400
  • 600
  • 704 a.a.
Protein Preferred Names Protein Names

neurolysin, mitochondrial

  • angiotensin binding protein

Recombinant NLN Proteins

Cat. No. Product Name Accession Purity
HY-P75938 Neurolysin Protein, Human (His) Q9BYT8 (S38-P704) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Senile Ectropion

  • Involutional Ectropion
Astigmatism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09345 NLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19567 Nln Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26063 Nln Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NLN RGD RGD:621518
Macaca mulatta NLN VGNC VGNC:75183
Felis catus NLN VGNC VGNC:63825
Mus musculus NLN MGD MGI:1923055
Bos taurus NLN VGNC VGNC:97293
Canis familiaris NLN VGNC VGNC:43842
Others NLN NCBI