Pglyrp2 - peptidoglycan recognition protein 2 Gene

Also Known as tagL; PGRP-L; Pglyrpl; C730002N09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57757

Summary

Predicted to enable N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding activity; and peptidoglycan immune receptor activity. Acts upstream of or within several processes, including negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation involved in immune response; and regulation of inflammatory response. Predicted to be located in extracellular region and membrane. Is expressed in hemolymphoid system and thymus primordium. Orthologous to human PGLYRP2 (peptidoglycan recognition protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Pglyrp2 Products (5)

mRNA Protein Name
NM_001271476.1 NP_001258405.1 N-acetylmuramoyl-L-alanine amidase isoform a precursor
NM_001271477.1 NP_001258406.1 N-acetylmuramoyl-L-alanine amidase isoform b precursor
NM_001271478.1 NP_001258407.1 N-acetylmuramoyl-L-alanine amidase isoform c precursor
NM_001271479.1 NP_001258408.1 N-acetylmuramoyl-L-alanine amidase isoform d precursor
NM_021319.5 NP_067294.2 N-acetylmuramoyl-L-alanine amidase isoform a precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within biological process involved in interaction with host IMP
IMP: Inferred from mutant phenotype
20709292 MGI
acts upstream of or within negative regulation of natural killer cell differentiation involved in immune response IMP
IMP: Inferred from mutant phenotype
20709292 MGI
acts upstream of or within negative regulation of type II interferon production IMP
IMP: Inferred from mutant phenotype
20709292 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: Inferred from mutant phenotype
19218085 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetylmuramoyl-L-alanine amidase

  • peptidoglycan recognition protein long

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10388 PGLYRP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20639 Pglyrp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27149 Pglyrp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pglyrp2 NCBI NCBI:114770