Mettl16 - methyltransferase like 16 Gene

Also Known as Mett10d; 2610100D03Rik; 2810013M15Rik; A830095F14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67493

Summary

Enables mRNA (N6-adenosine)-methyltransferase activity. Involved in mRNA catabolic process; mRNA destabilization; and mRNA methylation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human METTL16 (methyltransferase 16, N6-methyladenosine). [provided by Alliance of Genome Resources, Apr 2022]

Mettl16 Products (1)

mRNA Protein Name
NM_026197.3 NP_080473.1 RNA N6-adenosine-methyltransferase METTL16

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables mRNA m(6)A methyltransferase activity IDA
IDA: Inferred from direct assay
29262316 MGI
Biological Process GO Annotation Evidence References Source
involved in RNA methylation IDA
IDA: Inferred from direct assay
29262316 MGI
involved in mRNA catabolic process IDA
IDA: Inferred from direct assay
29262316 MGI
involved in mRNA destabilization IDA
IDA: Inferred from direct assay
29262316 MGI
involved in mRNA processing IMP
IMP: Inferred from mutant phenotype
30197299 MGI
involved in post-transcriptional regulation of gene expression IDA
IDA: Inferred from direct assay
29262316 MGI
NOT involved in regulation of mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
29262316 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA N6-adenosine-methyltransferase METTL16

  • N6-adenosine-methyltransferase METTL16

  • U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase

  • methyltransferase 10 domain containing

  • methyltransferase 10 domain-containing protein

  • methyltransferase-like protein 16

  • putative methyltransferase METT1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-161402 METTL16-IN-1 Inhibitor 99.22% Unkown
HY-162082 METTL1-WDR4-IN-2 Inhibitor 99.14% Unkown
HY-RS08357 METTL16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23843 Mettl16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17388 Mettl16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mettl16 NCBI NCBI:79066