Ecscr - endothelial cell surface expressed chemotaxis and apoptosis regulator Gene

Also Known as ARIA; 1110006O17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68545

Summary

Acts upstream of or within negative regulation of angiogenesis. Located in cytosol and plasma membrane. Is expressed in several structures, including extraembryonic component; gut; hemolymphoid system gland; male reproductive gland or organ; and respiratory system. Orthologous to human ECSCR (endothelial cell surface expressed chemotaxis and Apoptosis regulator). [provided by Alliance of Genome Resources, Apr 2022]

Ecscr Products (3)

mRNA Protein Name
NM_001033141.2 NP_001028313.1 endothelial cell-specific chemotaxis regulator isoform 3
NM_001368651.1 NP_001355580.1 endothelial cell-specific chemotaxis regulator isoform 1
NM_001368652.1 NP_001355581.1 endothelial cell-specific chemotaxis regulator isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
19416853 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
19416853 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19416853 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

endothelial cell-specific chemotaxis regulator

  • apoptosis regulator through modulating IAP expression

  • endothelial cell-specific molecule 2

Recombinant Ecscr Proteins

Cat. No. Product Name Accession Purity
HY-P77644 ECSCR Protein, Mouse (HEK293, Fc) Q3TZW0-1 (Q19-T130) ≥ 95%, as determined by Bis-Tris PAGE.

Orthologs Information

Species Symbol Source ID
Homo sapiens Ecscr NCBI NCBI:641700