2. Gene
  3. Haspin - histone H3 associated protein kinase Gene

Haspin - histone H3 associated protein kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gsg2

Gene ID: 687827 | Gene type: protein coding

About Haspin

Primary_assembly 10: 57,747,573-57,750,512 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 174 orthologues, 4 paralogues and is associated with 1 phenotype.

Summary

Predicted to enable ATP binding activity; DNA binding activity; and histone kinase activity (H3-T3 specific). Predicted to be involved in histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; intracellular signal transduction; and mitotic sister chromatid cohesion. Predicted to act upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Predicted to be located in centrosome; nucleoplasm; and spindle. Predicted to be active in cytoplasm and nucleus. Orthologous to human HASPIN (histone H3 associated protein kinase). [provided by Alliance of Genome Resources, Apr 2022]

Haspin Products(1)

mRNA Protein Name
NM_001398936.1 NP_001385865.1 histone H3 associated protein kinase

Haspin Protein Structure

PKc_like

PKc_like: cl21453 (361 - 743)

  • 0
  • 200
  • 400
  • 600
  • 751 a.a.
Protein Preferred Names Protein Names

histone H3 associated protein kinase

serine/threonine-protein kinase haspin

germ cell associated 2 (haspin)

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15424 5-Iodotubercidin Inhibitor 99.64% Unkown
HY-15217 CHR-6494 Inhibitor 98.07% Unkown
HY-13455 LDN-192960 Inhibitor 99.56% Unkown
HY-110320 LDN-209929 dihydrochloride Inhibitor ≥99.0% Unkown
HY-13455A LDN-192960 hydrochloride Inhibitor 99.78% Unkown
HY-146636 Haspin-IN-3 Inhibitor 98.14% Unkown
HY-110350 CHR-6494 TFA Inhibitor / Unkown
HY-146586 Haspin-IN-1 Inhibitor / Unkown
HY-146587 Haspin-IN-2 Inhibitor / Unkown
HY-155341 HSK205 Inhibitor / Unkown
HY-RS06009 HASPIN Human Pre-designed siRNA Set A / Unkown
HY-RS06010 Haspin Mouse Pre-designed siRNA Set A / Unkown
HY-RS06011 Haspin Rat Pre-designed siRNA Set A / Unkown
HY-100368 MELK-8a / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Haspin NCBI NCBI:83903