Haspin - histone H3 associated protein kinase Gene

Also Known as Gsg2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 687827

About Haspin

Primary_assembly 10: 57,747,573-57,750,512 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 174 orthologues, 4 paralogues and is associated with 1 phenotype.

Summary

Predicted to enable ATP binding activity; DNA binding activity; and histone kinase activity (H3-T3 specific). Predicted to be involved in histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; intracellular signal transduction; and mitotic sister chromatid cohesion. Predicted to act upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Predicted to be located in centrosome; nucleoplasm; and spindle. Predicted to be active in cytoplasm and nucleus. Orthologous to human HASPIN (histone H3 associated protein kinase). [provided by Alliance of Genome Resources, Apr 2022]

Haspin Products (1)

mRNA Protein Name
NM_001398936.1 NP_001385865.1 histone H3 associated protein kinase

Haspin Protein Structure

PKc_like

PKc_like: cl21453 (361 - 743)

  • 0
  • 200
  • 400
  • 600
  • 751 a.a.
Protein Preferred Names Protein Names

histone H3 associated protein kinase

serine/threonine-protein kinase haspin

  • germ cell associated 2 (haspin)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-30012 5-Bromo-7-azaindole 99.96% Phase 1

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15424 5-Iodotubercidin Inhibitor 99.95% Unkown
HY-15217 CHR-6494 Inhibitor 99.28% Unkown
HY-146636 Haspin-IN-3 Inhibitor 98.04% Unkown
HY-13455 LDN-192960 Inhibitor 99.58% Unkown
HY-13455A LDN-192960 hydrochloride Inhibitor 99.83% Unkown
HY-100368 MELK-8a 98.32% Unkown
HY-110320 LDN-209929 dihydrochloride Inhibitor 98.33% Unkown
HY-170546 MU1920 Inhibitor 98.22% Unkown
HY-110350 CHR-6494 TFA Inhibitor / Unkown
HY-146586 Haspin-IN-1 Inhibitor / Unkown
HY-146587 Haspin-IN-2 Inhibitor / Unkown
HY-155341 HSK205 Inhibitor 98.01% Unkown
HY-163858 Haspin-IN-4 Inhibitor / Unkown
HY-179486 Anticancer agent 285 Inhibitor / Unkown
HY-RS06009 HASPIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06010 Haspin Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06011 Haspin Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-112366 FLT3-IN-38 Inhibitor / Unkown
HY-135002 LDN-209929 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Haspin NCBI NCBI:83903