GLS - glutaminase Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 693520

About GLS

Primary_assembly 12: 78,100,570-78,185,152 forward strand.Mmul_10:CM014347.1

This gene has 2 transcripts (splice variants), 305 orthologues and 1 paralogue.

GLS Products (5)

mRNA Protein Name
XM_015110583.2 XP_014966069.2 glutaminase kidney isoform, mitochondrial isoform X1
XM_015110585.2 XP_014966071.2 glutaminase kidney isoform, mitochondrial isoform X3
XM_028830943.1 XP_028686776.1 glutaminase kidney isoform, mitochondrial isoform X5
XM_028830942.1 XP_028686775.1 glutaminase kidney isoform, mitochondrial isoform X4
XM_015110584.2 XP_014966070.2 glutaminase kidney isoform, mitochondrial isoform X2

GLS Protein Structure

EF-hand_14

EF-hand_14: pfam17959 (138 - 221)

Glutaminase

Glutaminase: pfam04960 (243 - 527)

Ank_2

Ank_2: pfam12796 (556 - 648)

ANK

ANK: sd00045 (556 - 582)

ANK

ANK: sd00045 (584 - 616)

  • 0
  • 200
  • 400
  • 600
  • 669 a.a.
Protein Preferred Names Protein Names

glutaminase kidney isoform, mitochondrial

  • glutaminase C

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-12248 Telaglenastat 99.82% Phase 2
HY-108917 Morphothiadin Inhibitor 99.79% Phase 2
HY-128357 Ibezapolstat Inhibitor 98.0% Phase 2
HY-12248A Telaglenastat hydrochloride 98.03% Phase 2
HY-P2760 Glutaminase Control / Phase 2
HY-108917A Morphothiadin mesylate Inhibitor / Phase 2
HY-128357A Ibezapolstat hydrochloride Inhibitor / Phase 2
HY-103671 IPN60090 Inhibitor 98.96% Phase 1
HY-103671A IPN60090 dihydrochloride Inhibitor 99.68% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99109 Zimberelimab Inhibitor 99.90% Phase 3

Pre-clinical Phase

Bioactive Molecules (20)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150109A Purinostat Inhibitor 98.04% Unkown
HY-136704 GLS1 Inhibitor-1 Inhibitor 98.59% Unkown
HY-79583 Glutaminase-IN-3 Inhibitor 99.88% Unkown
HY-144666 GLS-1-IN-1 Inhibitor 99.83% Unkown
HY-RS05500 GLS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-151434 GLS1 Inhibitor-6 / Unkown
HY-146616 GLS1 Inhibitor-3 Inhibitor / Unkown
HY-146617 GLS1 Inhibitor-4 / Unkown
HY-146658 Glutaminase-IN-4 Inhibitor / Unkown
HY-148241 A-446 Inhibitor / Unkown
HY-152207 LWG-301 / Unkown
HY-155138 GLS1 Inhibitor-7 Inhibitor / Unkown
HY-174211 JNK-IN-23 Inhibitor / Unkown
HY-179003 mTOR/GLS1-IN-1 / Unkown
HY-181890 TRG-192 Inhibitor / Unkown
HY-RS05501 Gls Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05502 Gls Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05503 GLS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17808 Gls2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24276 Gls2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990976 Brivestobart 99.198% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GLS NCBI NCBI:2744