Nptxr - neuronal pentraxin receptor Gene

Also Known as NPR; Npcd; D15Bwg0580e; 1200009K17Rik; 1700036C17Rik; 5730406O18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73340

Summary

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]

Nptxr Products (2)

mRNA Protein Name
NM_030689.4 NP_109614.2 neuronal pentraxin receptor
NM_030689.4 NP_109614.2 neuronal pentraxin receptor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein phosphatase binding IPI
IPI: Inferred from physical interaction
15673668 MGI
Biological Process GO Annotation Evidence References Source
involved in neuron projection development IMP
IMP: Inferred from mutant phenotype
15673668 MGI
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
27986928 MGI
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
27986928 MGI
involved in regulation of postsynaptic specialization assembly IDA
IDA: Inferred from direct assay
27986928 MGI
involved in regulation of postsynaptic specialization assembly IMP
IMP: Inferred from mutant phenotype
27986928 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27986928 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27986928 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15673668 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal pentraxin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09507 NPTXR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20067 Nptxr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26571 Nptxr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nptxr NCBI NCBI:23467