Slitrk1 - SLIT and NTRK-like family, member 1 Gene

Also Known as 3200001I04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76965

Summary

Acts upstream of or within several processes, including adult behavior; axonogenesis; and positive regulation of synapse assembly. Located in glutamatergic synapse. Is integral component of postsynaptic density membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; limb mesenchyme; and reproductive system. Used to study Gilles de la Tourette syndrome. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and trichotillomania. Orthologous to human SLITRK1 (SLIT and NTRK like family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slitrk1 Products (1)

mRNA Protein Name
NM_199065.2 NP_951020.1 SLIT and NTRK-like protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
36085162 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult behavior IMP
IMP: Inferred from mutant phenotype
18794888 MGI
acts upstream of or within axonogenesis IDA
IDA: Inferred from direct assay
14550773 MGI
acts upstream of or within endocytosis IMP
IMP: Inferred from mutant phenotype
36085162 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
36085162 MGI
acts upstream of or within homeostatic process IMP
IMP: Inferred from mutant phenotype
18794888 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
18794888 MGI
acts upstream of or within nervous system development IMP
IMP: Inferred from mutant phenotype
18794888 MGI
acts upstream of or within neuron projection extension IMP
IMP: Inferred from mutant phenotype
36085162 MGI
acts upstream of or within norepinephrine metabolic process IMP
IMP: Inferred from mutant phenotype
36085162 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
acts upstream of or within vocalization behavior IMP
IMP: Inferred from mutant phenotype
36085162 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27273464 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
27273464 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
27273464 MGI
is active in postsynaptic density membrane IEP
IEP: Inferred from expression pattern
27273464 MGI
located in synapse IDA
IDA: Inferred from direct assay
27273464 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLIT and NTRK-like protein 1

  • slit and trk like gene 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13373 SLITRK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20219 Slitrk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26726 Slitrk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slitrk1 NCBI NCBI:114798