IGFLR1 - IGF like family receptor 1 Gene

Also Known as TMEM149

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79713

About IGFLR1

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,738,801-35,742,452 (from NCBI)

This gene has 11 transcripts (splice variants) and 158 orthologues. Broad expression in lymph node (RPKM 16.7), spleen (RPKM 14.5) and 24 other tissues.

Summary

Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IGFLR1 Products (5)

mRNA Protein Name
NM_001346003.2 NP_001332932.1 IGF-like family receptor 1 isoform b precursor
NM_001346004.2 NP_001332933.1 IGF-like family receptor 1 isoform c precursor
NM_001346005.2 NP_001332934.1 IGF-like family receptor 1 isoform c precursor
NM_001346006.2 NP_001332935.1 IGF-like family receptor 1 isoform d precursor
NM_024660.4 NP_078936.1 IGF-like family receptor 1 isoform a precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21454693 GOA
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
21454693 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

IGF-like family receptor 1

  • transmembrane protein 149

IGFLR1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IGFLR1 Q9H665 IGFL1 Homo sapiens Q6UW32
FACS
21454693
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant IGFLR1 Proteins

Cat. No. Product Name Accession Purity
HY-P77396 IGFLR1 Protein, Human (HEK293, Fc) Q9H665-1 (S23-P159) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700454 IGFLR1 Protein, Human (HEK293, C-His) Q9H665-1 (S23-P163) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06635 IGFLR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20166 Igflr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26670 Igflr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus IGFLR1 VGNC VGNC:30091
Mus musculus IGFLR1 MGD MGI:3655979
Macaca mulatta IGFLR1 VGNC VGNC:73434
Rattus norvegicus IGFLR1 RGD RGD:1563574
Canis familiaris IGFLR1 VGNC VGNC:41909
Others IGFLR1 NCBI