ADM2 - adrenomedullin 2 Gene

Homo sapiens

Also known as AM2; dJ579N16.4

Gene ID: 79924 | Gene type: protein coding

About ADM2

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,481,543-50,486,437 (from NCBI)

This gene has 2 transcripts (splice variants), 222 orthologues and 1 paralogue. Biased expression in thyroid (RPKM 8.0), kidney (RPKM 5.1) and 12 other tissues.

Summary

This gene encodes a member of the Calcitonin gene-related peptide (CGRP)/Calcitonin family of Hormones that play a role in the regulation of cardiovascular homeostasis, Prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active Peptides. [provided by RefSeq, Jul 2015]

ADM2 Products(2)

mRNA	Protein	Name
NM_001253845.2	NP_001240774.1	protein ADM2 preproprotein
NM_001369882.1	NP_001356811.1	protein ADM2 preproprotein

ADM2 Protein Structure

Calc_CGRP_IAPP

0
100
148 a.a.

Protein Preferred Names

Protein Names

protein ADM2

intermedin

Related Diseases

Diseases

Alias

Immunodeficiency 53

IMD53

Coronary Stenosis

Coronary Artery Stenosis

Charcot-Marie-Tooth Disease, X-Linked Recessive, 3

CMTX3	Charcot-Marie-Tooth Disease X-Linked Recessive 3
Charcot-Marie-Tooth Neuropathy, X-Linked Recessive, 3	Cmt3x
X-Linked Charcot-Marie-Tooth Disease Type 3	Charcot-Marie-Tooth Neuropathy X-Linked Recessive 3
Charcot-Marie-Tooth Disease, X-Linked Type 3, Recessive

Myopathy, Centronuclear, 2

Myopathy, Centronuclear, Autosomal Recessive	Autosomal Recessive Centronuclear Myopathy
CNM2	Centronuclear Myopathy 2
Ar-Cnm	Myotubular Myopathy, Autosomal Recessive
Autosomal Recessive Myotubular Myopathy	Centronuclear Myopathy Autosomal Recessive
Myopathy, Centronuclear, Type 2

Epiphyseal Dysplasia, Multiple, 1

EDM1	Multiple Epiphyseal Dysplasia 1
Multiple Epiphyseal Dysplasia Type 1	Med1
Multiple Epiphyseal Dysplasia Comp-Related	Polyepiphyseal Dysplasia Type 1
Multiple Epiphyseal Dysplasia, Comp-Related	Epiphyseal Dysplasia Multiple 1
Epiphyseal Dysplasia, Multiple 1	Dysplasia, Epiphyseal, Multiple, Type 1

Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly

Migraine With Or Without Aura 1

Migraine	Migraine With Or Without Aura, Susceptibility To, 1
Migraine Disorder	Migraine Variant
Migraines	Migraine Disorders
Mgr1	Mgau
Ma	Migraine With Or Without Aura
Classic Migraine	Common Migraine
Disorder, Migraine	Headache Migraine
Headache Migrainous	Migraine Headache
Migraine Syndrome	Headache Including Migraine
Migraine, Susceptibility To

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0876	Arenobufagin	Inhibitor	99.86%	Unkown
HY-N1514	Ganoderenic acid B		99.61%	Unkown
HY-RS00387	ADM2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ADM2	VGNC	VGNC:37661
Felis catus	ADM2	VGNC	VGNC:83486
Macaca mulatta	ADM2	VGNC	VGNC:107731
Mus musculus	ADM2	MGD	MGI:2675256
Bos taurus	ADM2	VGNC	VGNC:25682
Rattus norvegicus	ADM2	RGD	RGD:1302971
Others	ADM2	NCBI

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