ADM2 - adrenomedullin 2 Gene

Also Known as AM2; dJ579N16.4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79924

About ADM2

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,481,543-50,486,437 (from NCBI)

This gene has 2 transcripts (splice variants), 222 orthologues and 1 paralogue. Biased expression in thyroid (RPKM 8.0), kidney (RPKM 5.1) and 12 other tissues.

Summary

This gene encodes a member of the Calcitonin gene-related peptide (CGRP)/Calcitonin family of Hormones that play a role in the regulation of cardiovascular homeostasis, Prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015]

ADM2 Products (2)

mRNA Protein Name
NM_001253845.2 NP_001240774.1 protein ADM2 preproprotein
NM_001369882.1 NP_001356811.1 protein ADM2 preproprotein

ADM2 Protein Structure

Calc_CGRP_IAPP

Calc_CGRP_IAPP: Calcitonin / CGRP / IAPP family (104 - 148)

  • 0
  • 100
  • 148 a.a.
Protein Preferred Names Protein Names

protein ADM2

  • intermedin

Related Diseases

Diseases Alias
Immunodeficiency 53

  • IMD53
Coronary Stenosis

  • Coronary Artery Stenosis
Charcot-Marie-Tooth Disease, X-Linked Recessive, 3

  • CMTX3

  • Charcot-Marie-Tooth Disease X-Linked Recessive 3

  • Charcot-Marie-Tooth Neuropathy, X-Linked Recessive, 3

  • Cmt3x

  • X-Linked Charcot-Marie-Tooth Disease Type 3

  • Charcot-Marie-Tooth Neuropathy X-Linked Recessive 3

  • Charcot-Marie-Tooth Disease, X-Linked Type 3, Recessive
Myopathy, Centronuclear, 2

  • Myopathy, Centronuclear, Autosomal Recessive

  • Autosomal Recessive Centronuclear Myopathy

  • CNM2

  • Centronuclear Myopathy 2

  • Ar-Cnm

  • Myotubular Myopathy, Autosomal Recessive

  • Autosomal Recessive Myotubular Myopathy

  • Centronuclear Myopathy Autosomal Recessive

  • Myopathy, Centronuclear, Type 2
Epiphyseal Dysplasia, Multiple, 1

  • EDM1

  • Multiple Epiphyseal Dysplasia 1

  • Multiple Epiphyseal Dysplasia Type 1

  • Med1

  • Multiple Epiphyseal Dysplasia Comp-Related

  • Polyepiphyseal Dysplasia Type 1

  • Multiple Epiphyseal Dysplasia, Comp-Related

  • Epiphyseal Dysplasia Multiple 1

  • Epiphyseal Dysplasia, Multiple 1

  • Dysplasia, Epiphyseal, Multiple, Type 1
Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly
Migraine With Or Without Aura 1

  • Migraine

  • Migraine With Or Without Aura, Susceptibility To, 1

  • Migraine Disorder

  • Migraine Variant

  • Migraines

  • Migraine Disorders

  • Mgr1

  • Mgau

  • Ma

  • Migraine With Or Without Aura

  • Classic Migraine

  • Common Migraine

  • Disorder, Migraine

  • Headache Migraine

  • Headache Migrainous

  • Migraine Headache

  • Migraine Syndrome

  • Headache Including Migraine

  • Migraine, Susceptibility To
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0876 Arenobufagin Inducer 99.82% Unkown
HY-N1514 Ganoderenic acid B 99.95% Unkown
HY-RS00387 ADM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20246 Adm2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26754 Adm2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ADM2 VGNC VGNC:37661
Felis catus ADM2 VGNC VGNC:83486
Macaca mulatta ADM2 VGNC VGNC:107731
Mus musculus ADM2 MGD MGI:2675256
Bos taurus ADM2 VGNC VGNC:25682
Rattus norvegicus ADM2 RGD RGD:1302971
Others ADM2 NCBI