IQCG - IQ motif containing G Gene

Also Known as DRC9; CFAP122

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84223

About IQCG

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:197,889,077-197,960,177 (from NCBI)

This gene has 13 transcripts (splice variants) and 153 orthologues. Broad expression in testis (RPKM 19.6), ovary (RPKM 6.1) and 20 other tissues.

Summary

Enables HSP70 protein binding activity and Calmodulin binding activity. Predicted to be involved in sperm axoneme assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

IQCG Products (6)

mRNA Protein Name
NM_001134435.3 NP_001127907.1 dynein regulatory complex protein 9 isoform a
NM_001323027.2 NP_001309956.1 dynein regulatory complex protein 9 isoform a
NM_001323028.2 NP_001309957.1 dynein regulatory complex protein 9 isoform b
NM_001323029.2 NP_001309958.1 dynein regulatory complex protein 9 isoform c
NM_001323030.2 NP_001309959.1 dynein regulatory complex protein 9 isoform d
NM_032263.5 NP_115639.1 dynein regulatory complex protein 9 isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables Hsp70 protein binding IPI
IPI: Inferred from physical interaction
24787902 GOA
enables calmodulin binding IDA
IDA: Inferred from direct assay
24787902 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24787902 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IQCG Protein Structure

IQ

IQ: IQ calmodulin-binding motif (395 - 412)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 443 a.a.
Protein Preferred Names Protein Names

dynein regulatory complex protein 9

  • IQ domain-containing protein G

Related Diseases

Diseases Alias
Diamond-Blackfan Anemia 5

  • DBA5

  • Rpl35a-Related Diamond-Blackfan Anemia

  • Anemia, Diamond-Blackfan, Type 5
Alveoli Adenoma

  • Alveolar Adenoma

  • Adenoma Of Alveoli

  • Adenoma Of The Alveoli
Bronchial Benign Neoplasm

  • Bronchus Neoplasm

  • Neoplasm Of Bronchus

  • Bronchial Neoplasms

  • Bronchial Neoplasm
Primary Ciliary Dyskinesia

  • Immotile Cilia Syndrome

  • Kartagener Syndrome

  • Dextrocardia Bronchiectasis And Sinusitis

  • Pcd

  • Ciliary Motility Disorders

  • Ciliary Motility Disorder

  • Immotile Ciliary Syndrome

  • Ciliary Dyskinesia Primary

  • Ics

  • Polynesian Bronchiectasis

  • Dextrocardia-Bronchiectasis-Sinusitis Syndrome

  • Immotile Cilia Syndrome, Kartagener Type

  • Primary Ciliary Dyskinesia And Situs Inversus

  • Primary Ciliary Dyskinesia, Kartagener Type

  • Siewert Syndrome

  • Dyskinesia, Ciliary, Primary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06879 IQCG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19610 Iqcg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26105 Iqcg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IQCG RGD RGD:1311606
Mus musculus IQCG MGD MGI:1916957
Felis catus IQCG VGNC VGNC:62964
Macaca mulatta IQCG VGNC VGNC:73649
Bos taurus IQCG VGNC VGNC:30256
Canis familiaris IQCG VGNC VGNC:42079
Others IQCG NCBI