HAGHL - hydroxyacylglutathione hydrolase like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84264

About HAGHL

This gene has 20 transcripts (splice variants), 159 orthologues and 4 paralogues. Broad expression in brain (RPKM 1.8), spleen (RPKM 1.6) and 20 other tissues.

Summary

Predicted to enable hydroxyacylglutathione hydrolase activity and metal ion binding activity. Predicted to be involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. [provided by Alliance of Genome Resources, Apr 2022]

HAGHL Products (7)

mRNA Protein Name
NM_001290137.2 NP_001277066.1 hydroxyacylglutathione hydrolase-like protein isoform 2
NM_001290139.2 NP_001277068.1 hydroxyacylglutathione hydrolase-like protein isoform 2
NM_001323635.2 NP_001310564.1 hydroxyacylglutathione hydrolase-like protein isoform 2
NM_001323636.2 NP_001310565.1 hydroxyacylglutathione hydrolase-like protein isoform 3
NM_001365282.1 NP_001352211.1 hydroxyacylglutathione hydrolase-like protein isoform 4
NM_032304.4 NP_115680.1 hydroxyacylglutathione hydrolase-like protein isoform 2
NM_207112.2 NP_996995.1 hydroxyacylglutathione hydrolase-like protein isoform 1

HAGHL Protein Structure

Lactamase_B

Lactamase_B: Metallo-beta-lactamase superfamily (10 - 172)

  • 0
  • 100
  • 200
  • 290 a.a.
Protein Preferred Names Protein Names

hydroxyacylglutathione hydrolase-like protein

  • GLO2-like/ RJD12

HAGHL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HAGHL Q6PII5 FKBP1A Homo sapiens Q0VDC6
Validated Y2H
32814053
Intra
HAGHL Q6PII5 FKBP1A Homo sapiens Q0VDC6
Y2H Array
32814053
Intra
HAGHL Q6PII5 FKBP1A Homo sapiens Q0VDC6
Y2H Pooling
32814053
Intra
HAGHL Q6PII5 PMP22 Homo sapiens A0A6Q8PF08
Validated Y2H
32814053
Intra
HAGHL Q6PII5 PMP22 Homo sapiens A0A6Q8PF08
Y2H Array
32814053
Intra
HAGHL Q6PII5 PMP22 Homo sapiens A0A6Q8PF08
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Nemaline Myopathy 1

  • Cap Myopathy 1

  • NEM1

  • Nemaline Myopathy 1, Autosomal Dominant Or Recessive

  • Nemaline Myopathy, Type 1

  • CAPM1

  • Cap Disease

  • Cap Myopathy Tpm3-Related

  • Nemaline Myopathy 1 Autosomal Dominant Or Recessive

  • Myopathy, Nemaline, Type 1

  • Cap Myopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05993 HAGHL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HAGHL VGNC VGNC:73167
Rattus norvegicus HAGHL RGD RGD:1308042
Bos taurus HAGHL VGNC VGNC:29743
Mus musculus HAGHL MGD MGI:1919877
Felis catus HAGHL VGNC VGNC:62750
Canis familiaris HAGHL VGNC VGNC:41586