Tmed10 - transmembrane p24 trafficking protein 10 Gene

Also Known as Tmp21

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84599

Summary

Predicted to enable protein transmembrane transporter activity and syntaxin binding activity. Involved in several processes, including Golgi organization; response to alkaloid; and vesicle targeting, to, from or within Golgi. Located in several cellular components, including Golgi apparatus; cytoplasmic vesicle; and endoplasmic reticulum-Golgi intermediate compartment. Is integral component of membrane. Part of gamma-secretase complex. Orthologous to human TMED10 (transmembrane p24 trafficking protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Tmed10 Products (1)

mRNA Protein Name
NM_053467.1 NP_445919.1 transmembrane emp24 domain-containing protein 10 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11739402 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
10214941 RGD
Biological Process GO Annotation Evidence References Source
involved in Golgi organization IMP
IMP: Inferred from mutant phenotype
9914165 RGD
involved in kidney development IEP
IEP: Inferred from expression pattern
10893644 RGD
involved in regulated exocytosis IEP
IEP: Inferred from expression pattern
17101722 RGD
involved in response to alkaloid IEP
IEP: Inferred from expression pattern
9288726 RGD
involved in vesicle targeting, to, from or within Golgi IEP
IEP: Inferred from expression pattern
17101722 RGD
Cellular Component GO Annotation Evidence References Source
located in COPI-coated vesicle IDA
IDA: Inferred from direct assay
10214941 RGD
located in Golgi membrane IDA
IDA: Inferred from direct assay
31455601 RGD
located in cis-Golgi network IDA
IDA: Inferred from direct assay
17101722 RGD
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
9914165 RGD
part of gamma-secretase complex IDA
IDA: Inferred from direct assay
19754663 RGD
located in membrane IDA
IDA: Inferred from direct assay
8663407 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
18627576 RGD
located in zymogen granule membrane IDA
IDA: Inferred from direct assay
8663407 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane emp24 domain-containing protein 10

  • 21 kDa transmembrane-trafficking protein

  • integral membrane protein Tmp21-I (p23)

  • p24 family protein delta-1

  • p24delta1

  • transmembrane emp24-like trafficking protein 10

  • transmembrane protein Tmp21

  • transmembrane trafficking protein 21

Tmed10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tmed10 Q63584 Gorasp2 Rattus norvegicus Q9R064
Pull Down
11739402
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14635 TMED10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19272 Tmed10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25761 Tmed10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmed10 NCBI NCBI:10972