CREG1 - cellular repressor of E1A stimulated genes 1 Gene

Also Known as CREG

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8804

About CREG1

Cytogenetic location: 1q24.2 Genomic coordinates (GRCh38): 1:167,541,013-167,553,762 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in gall bladder (RPKM 83.3), thyroid (RPKM 78.7) and 25 other tissues.

Summary

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008]

CREG1 Products (1)

mRNA Protein Name
NM_003851.3 NP_003842.1 protein CREG1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
25645918 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CREG1 Protein Structure

Pyrid_oxidase_2

Pyrid_oxidase_2: Pyridoxamine 5'-phosphate oxidase (50 - 216)

  • 0
  • 100
  • 200
  • 220 a.a.
Protein Preferred Names Protein Names

protein CREG1

Recombinant CREG1 Proteins

Cat. No. Product Name Accession Purity
HY-P7849 CREG1/CREG Protein, Human (HEK293, His) O75629 (R32-Q220) ≥ 95%, as determined by reducing SDS-PAGE.

CREG1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810163 CREG Antibody (YA9507) WB, ICC/IF, IF-Tissue, IHC-P, IP, ELISA human
HY-P811009 CREG1 Antibody WB, IHC-P Human, Mouse, Rat

Related Diseases

Diseases Alias
Embryonal Carcinoma

  • Embryonal Neoplasm

  • Embryonal Cancer

  • Primary Extragonadal Embryonal Carcinoma

  • Embryo Neoplasm

  • Carcinoma Embryonal

  • Cancer Embryonal

  • Carcinoma, Embryonal

  • Extragonadal Embryonal Carcinoma

  • Cancer, Embryonal
Ornithosis

  • Psittacosis

  • Chlamydial Pneumonia

  • Chlamydia Psittaci Infection

  • Chlamydia Psittaci
Spondyloarthropathy

  • Spondylarthropathies

  • Spondarthropathy

  • Spondylarthrosis

  • Spondyloarthropathy, Susceptibility To

  • Spondylarthritis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03161 CREG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19424 Creg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25915 Creg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CREG1 VGNC VGNC:61174
Canis familiaris CREG1 VGNC VGNC:39605
Bos taurus CREG1 VGNC VGNC:27702
Macaca mulatta CREG1 VGNC VGNC:106346
Rattus norvegicus CREG1 RGD RGD:1306804
Mus musculus CREG1 MGD MGI:1344382
Others CREG1 NCBI