GMFG - glia maturation factor gamma Gene
Also Known as GMF-GAMMA
Species: Homo sapiens
About GMFG
This gene has 12 transcripts (splice variants), 178 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 133.3), spleen (RPKM 93.4) and 15 other tissues.
Summary
Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in extracellular region; ficolin-1-rich granule lumen; and secretory granule lumen. [provided by Alliance of Genome Resources, Apr 2022]
GMFG Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001301008.2 | NP_001287937.1 | glia maturation factor gamma isoform 2 |
| NM_001411106.1 | NP_001398035.1 | glia maturation factor gamma isoform 3 |
| NM_004877.4 | NP_004868.1 | glia maturation factor gamma isoform 1 |
GMFG Protein Structure
Cofilin_ADF: Cofilin/tropomyosin-type actin-binding protein (13 - 138)
- 0
- 100
- 142 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
glia maturation factor gamma |
|
Recombinant GMFG Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P76367 | GMFG Protein, Human (His) | O60234 (S2-R142) | ≥ 95%, as determined by reducing SDS-PAGE. |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | GMFG | RGD | RGD:620506 |
| Canis familiaris | GMFG | VGNC | VGNC:53720 |
| Macaca mulatta | GMFG | VGNC | VGNC:73080 |
| Mus musculus | GMFG | MGD | MGI:1927135 |
| Bos taurus | GMFG | VGNC | VGNC:29435 |
| Others | GMFG | NCBI |