2. Gene
  3. ENTPD3 - ectonucleoside triphosphate diphosphohydrolase 3 Gene

ENTPD3 - ectonucleoside triphosphate diphosphohydrolase 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HB6; CD39L3; NTPDase-3

Gene ID: 956 | Gene type: protein coding

About ENTPD3

Cytogenetic location: 3p22.1 Genomic coordinates (GRCh38): 3:40,387,184-40,428,744 (from NCBI)

This gene has 5 transcripts (splice variants), 202 orthologues and 7 paralogues. Broad expression in urinary bladder (RPKM 4.1), thyroid (RPKM 2.0) and 20 other tissues.

Summary

This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]

ENTPD3 Products(3)

mRNA Protein Name
NM_001248.4 NP_001239.2 ectonucleoside triphosphate diphosphohydrolase 3 isoform 1
NM_001291960.2 NP_001278889.1 ectonucleoside triphosphate diphosphohydrolase 3 isoform 1
NM_001291961.2 NP_001278890.1 ectonucleoside triphosphate diphosphohydrolase 3 isoform 2

ENTPD3 Protein Structure

GDA1_CD39

GDA1_CD39: GDA1/CD39 (nucleoside phosphatase) family (55 - 474)

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  • 529 a.a.
Protein Preferred Names Protein Names

ectonucleoside triphosphate diphosphohydrolase 3

CD39 antigen-like 3

Recombinant ENTPD3 Proteins

Cat. No. Product Name Accession Purity
HY-P76904 ENTPD3 Protein, Human (sf9, His) O75355 (Q44-P485) ≥95%

Related Diseases

Diseases Alias
Vasculogenic Impotence

Impotence, Vasculogenic
Purulent Labyrinthitis

Suppurative Labyrinthitis

Acute Suppurative Labyrinthitis

Bacterial Labyrinthitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04397 ENTPD3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ENTPD3 VGNC VGNC:72226
Rattus norvegicus ENTPD3 RGD RGD:631326
Bos taurus ENTPD3 VGNC VGNC:28510
Mus musculus ENTPD3 MGD MGI:1321386
Canis familiaris ENTPD3 VGNC VGNC:40382
Felis catus ENTPD3 VGNC VGNC:61880
Others ENTPD3 NCBI