Glucocorticoid receptor/NF-κB modulator-1
Glucocorticoid receptor/NF-κB modulator-1 (Compound 20) is a derivative of ocotillol. Glucocorticoid receptor/NF-κB modulator-1 suppresses the degradation of glucocorticoid receptor (GR) mRNA and GR protein, inhibits the activation of NF-κB signaling pathway. Glucocorticoid receptor/NF-κB modulator-1 downregulates levels of NO, interleukin-6 and tumor necrosis factor-alpha (TNF-α). Glucocorticoid receptor/NF-κB modulator-1 ameliorates sepsis in mouse model.
For research use only. We do not sell to patients.
- Formula: C39H62N2O6S
- Molecular Weight:686.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 686.98
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Formula C39H62N2O6S
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SMILES
[H][C@@]12[C@](CC[C@@H]2[C@]3(C)CC[C@@H](C(C)(O)C)O3)(C)[C@]4(C)CC[C@@]5([H])C(C)(C)C6=C(SC(NC(CCC(OC(C)(C)C)=O)=O)=N6)C[C@]5(C)[C@@]4([H])C[C@H]1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)