Guretolimod hydrochloride
Based on 1 Customer Validation
Guretolimod hydrochloride is a Toll-like receptor 7 (TLR7) agonist.
For research use only. We do not sell to patients.
- Purity: 98.67%
- Formula: C24H35ClF3N5O4
- Molecular Weight:550.01
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
TLR7[1]
Chemical Information
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Appearance Solid
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Molecular Weight 550.01
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Formula C24H35ClF3N5O4
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Color Off-white to light yellow
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SMILES
CCC[C@@H](CCO)NC1=NC(N)=NC(C)=C1CC2=C(C=C(C=C2)CN(CC(O)=O)CC(F)(F)F)OC.Cl
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Synonyms
DSP-0509 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (181.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8181 mL | 9.0907 mL | 18.1815 mL | 45.4537 mL |
| 5 mM | 0.3636 mL | 1.8181 mL | 3.6363 mL | 9.0907 mL | |
| 10 mM | 0.1818 mL | 0.9091 mL | 1.8181 mL | 4.5454 mL | |
| 15 mM | 0.1212 mL | 0.6060 mL | 1.2121 mL | 3.0302 mL | |
| 20 mM | 0.0909 mL | 0.4545 mL | 0.9091 mL | 2.2727 mL | |
| 25 mM | 0.0727 mL | 0.3636 mL | 0.7273 mL | 1.8181 mL | |
| 30 mM | 0.0606 mL | 0.3030 mL | 0.6060 mL | 1.5151 mL | |
| 40 mM | 0.0455 mL | 0.2273 mL | 0.4545 mL | 1.1363 mL | |
| 50 mM | 0.0364 mL | 0.1818 mL | 0.3636 mL | 0.9091 mL | |
| 60 mM | 0.0303 mL | 0.1515 mL | 0.3030 mL | 0.7576 mL | |
| 80 mM | 0.0227 mL | 0.1136 mL | 0.2273 mL | 0.5682 mL | |
| 100 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4545 mL |