1. Anti-infection
  2. HCV
  3. HCV Peptide (35-44)

HCV Peptide (35-44), a HCV core protein at positions 35 to 44, is a HLA-A2-restricted CTL epitope. HCV Peptide (35-44) inhibits NK cell activity via two distinct mechanisms, directly via KIR2DL2/3, and synergistically via the CD94:NKG2A receptor.

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Custom Peptide Synthesis

HCV Peptide (35-44) Chemical Structure

HCV Peptide (35-44) Chemical Structure

CAS No. : 160214-01-7

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5 mg USD 70 In-stock
10 mg USD 110 In-stock
25 mg USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

HCV Peptide (35-44), a HCV core protein at positions 35 to 44, is a HLA-A2-restricted CTL epitope. HCV Peptide (35-44) inhibits NK cell activity via two distinct mechanisms, directly via KIR2DL2/3, and synergistically via the CD94:NKG2A receptor[1].

In Vitro

HCV Peptide (35-44) (0-100 μM) inhibits degranulation of the total NK cell population. HCV Peptide (35-44) increases cell surface expression of both HLA-C and HLA-E[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1240.50

Formula

C57H97N19O12

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

YLLPRRGPRL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (80.61 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8061 mL 4.0306 mL 8.0613 mL
5 mM 0.1612 mL 0.8061 mL 1.6123 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8061 mL 4.0306 mL 8.0613 mL 20.1532 mL
5 mM 0.1612 mL 0.8061 mL 1.6123 mL 4.0306 mL
10 mM 0.0806 mL 0.4031 mL 0.8061 mL 2.0153 mL
15 mM 0.0537 mL 0.2687 mL 0.5374 mL 1.3435 mL
20 mM 0.0403 mL 0.2015 mL 0.4031 mL 1.0077 mL
25 mM 0.0322 mL 0.1612 mL 0.3225 mL 0.8061 mL
30 mM 0.0269 mL 0.1344 mL 0.2687 mL 0.6718 mL
40 mM 0.0202 mL 0.1008 mL 0.2015 mL 0.5038 mL
50 mM 0.0161 mL 0.0806 mL 0.1612 mL 0.4031 mL
60 mM 0.0134 mL 0.0672 mL 0.1344 mL 0.3359 mL
80 mM 0.0101 mL 0.0504 mL 0.1008 mL 0.2519 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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HCV Peptide (35-44) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HCV Peptide (35-44)
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