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Cat. No.: HY-P11724

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Histone H4 peptide substrate (1-21)

Histone H4 peptide substrate (1-21) is a PAD4 peptide substrate. Histone H4 peptide substrate (1-21) serves as a substrate for the PAD4-catalyzed hydrolytic deimination of arginine residues, producing citrulline and ammonia.

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CAS No.: 374899-66-8
Formule: C₈₇H₁₅₉N₃₇O₂₃
Masse moléculaire:2091.43

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Please store the product under the recommended conditions in the Certificate of Analysis.

Histone H4 peptide substrate (1-21) Chemical Structure

CAS No.: 374899-66-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Classifications
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Activité biologique

Description

In Vitro

Histone H4 peptide substrate (1-21) (Compound H4-21) undergoes deimination catalyzed by purified recombinant human PAD4, exhibiting steady-state kinetic parameters comparable to those of benzoylated arginine derivatives^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 374899-66-8
Masse moléculaire 2091.43
Formule C₈₇H₁₅₉N₃₇O₂₃
SMILES

O=C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C(NCC(NCC(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(NCC(NCC(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Sequence

Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val
Sequence Shortening

SGRGKGGKGLGKGGAKRHRKV
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Kearney PL, et al. Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis. Biochemistry. 2005;44(31):10570-10582. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Histone H4 peptide substrate (1-21)

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Activité biologique
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Chemical Information
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Histone H4 peptide substrate (1-21)

Activité biologique

Description

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Histone H4 peptide substrate (1-21) Related Classifications

HY-P11724 Related Classifications

Bioz

Keywords

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