country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P11724

Copy Link Print Information

Histone H4 peptide substrate (1-21)

Histone H4 peptide substrate (1-21) is a PAD4 peptide substrate. Histone H4 peptide substrate (1-21) serves as a substrate for the PAD4-catalyzed hydrolytic deimination of arginine residues, producing citrulline and ammonia.

For research use only. We do not sell to patients.

CAS No.: 374899-66-8
Formula: C₈₇H₁₅₉N₃₇O₂₃
Molecular Weight:2091.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Histone H4 peptide substrate (1-21) Chemical Structure

CAS No.: 374899-66-8

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Histone H4 peptide substrate (1-21) (Compound H4-21) undergoes deimination catalyzed by purified recombinant human PAD4, exhibiting steady-state kinetic parameters comparable to those of benzoylated arginine derivatives^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 374899-66-8
Molecular Weight 2091.43
Formula C₈₇H₁₅₉N₃₇O₂₃
SMILES

O=C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C(NCC(NCC(N[C@@H](CCCCN)C(NCC(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(NCC(NCC(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Sequence

Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val
Sequence Shortening

SGRGKGGKGLGKGGAKRHRKV
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kearney PL, et al. Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis. Biochemistry. 2005;44(31):10570-10582. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Histone H4 peptide substrate (1-21)

100 mg Get Quote

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Histone H4 peptide substrate (1-21)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Histone H4 peptide substrate (1-21) Related Classifications

HY-P11724 Related Classifications