HIV-1 inhibitor-33
HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor with an EC50 of 8.6 nM for HIV-1 and a CC50 of 18 μM in MT-4 cells. HIV-1 inhibitor-33 can be used for researching AIDS.
For research use only. We do not sell to patients.
- CAS No.: 2395777-43-0
- Formula: C25H28N6O
- Molecular Weight:428.53
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
HIV-1 (WT) 8.6 nM (EC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
18 μM
Compound: 5n
|
Cytotoxicity against human MT4 cells assessed as inhibition of cell viability by measuring reduction in absorbance at OD540 by MTT assay
Cytotoxicity against human MT4 cells assessed as inhibition of cell viability by measuring reduction in absorbance at OD540 by MTT assay
|
[PMID: 31767136] |
Chemical Information
-
CAS No. 2395777-43-0
-
Molecular Weight 428.53
-
Formula C25H28N6O
-
SMILES
CC(C=CC=C1C)=C1OC2=CC=NC(NC3CCN(CC3)CC4=NNC5=C4C=CC=C5)=N2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)