HIV-1 inhibitor-35
HIV-1 inhibitor-35 (compound 74) is a potent HIV-1 inhibitor with EC50s of 80 nM and 70 nM for LTR and CMV in HEK293 cells, respectively. HIV-1 inhibitor-35 has inhibitory activity against liver cancer cell HepG2 with a CC50 of 40 nM. HIV-1 inhibitor-35 can be used as HIV-1 latency reversing agent.
For research use only. We do not sell to patients.
- CAS No.: 2416971-32-7
- Formula: C13H12Cl3N5OS
- Molecular Weight:392.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
HIV-1[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
0.04 μM
Compound: 74
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Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay
Cytotoxicity against human HepG2 cells assessed as growth incubation incubated for 48 hrs by cell titer glo assay
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[PMID: 32251744] |
Chemical Information
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CAS No. 2416971-32-7
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Molecular Weight 392.69
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Formula C13H12Cl3N5OS
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SMILES
O=C(N1CCN(CC1)C2=CN=C(C(Cl)=C2)Cl)NC3=NC=C(S3)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HIV-1 inhibitor-35 Related Classifications
HY-147552 Related Classifications
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