2230055-52-2
2230055-52-2
Chemical Structure
PKCiota-IN-2
- CAS No.: 2230055-52-2
- Formula:C24H21N5O
- Molecular Weight:395.46
IUPAC Name: 7-(5-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrazolo[1,5-a]pyridin-3-yl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline
InChIKey: PHOVPHVCAJYUNY-UHFFFAOYSA-N
SMILES: COC1=CC2=C(CNCC2)C=C1C3=C4C=C(C5=C6C(NC=C6)=NC=C5)C=CN4N=C3
Biological Activity: PKCiota-IN-2 (Compound 49) is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively[1].
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PKCiota-IN-2 | PKCiota-IN-2 (Compound 49) is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively. | |||||||||||||||||||||
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