1. Immunology/Inflammation
  2. IRAK
  3. IRAK1/4/pan-FLT3 Kinase-IN-2

IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent IRAK1/4 and FLT3 dual inhibitor with IC50s of 10, 0.7, and <0.5 nM. IRAK1/4/pan-FLT3 Kinase-IN-2 extends acute myeloid leukemia model mouse survival.

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IRAK1/4/pan-FLT3 Kinase-IN-2

IRAK1/4/pan-FLT3 Kinase-IN-2 화학구조

CAS No. : 2760329-44-8

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제품 설명

IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent IRAK1/4 and FLT3 dual inhibitor with IC50s of 10, 0.7, and <0.5 nM. IRAK1/4/pan-FLT3 Kinase-IN-2 extends acute myeloid leukemia model mouse survival[1].

분자량

405.42

화학식

C20H22F3N5O

CAS No.
SMILES

CC(C)OC1=CC2=NC=C(C3=C(F)C=C(F)C(N[C@H]4CNCC[C@@H]4F)=N3)N2C=C1

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
IRAK1/4/pan-FLT3 Kinase-IN-2
Cat. No.:
HY-176410
수량:
MCE Japan Authorized Agent: