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AURKAIP1 - aurora kinase A interacting protein 1 Gene

Also Known as AIP; AKIP; MRP-S38

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 54998

About AURKAIP1

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,373,736-1,375,207 (from NCBI)

This gene has 6 transcripts (splice variants) and 189 orthologues. Ubiquitous expression in testis (RPKM 40.0), kidney (RPKM 27.3) and 25 other tissues.

Summary

Acts upstream of or within positive regulation of proteolysis. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

AURKAIP1 Products (3)

mRNA	Protein	Name
NM_001127229.2	NP_001120701.1	aurora kinase A-interacting protein
NM_001127230.2	NP_001120702.1	aurora kinase A-interacting protein
NM_017900.3	NP_060370.1	aurora kinase A-interacting protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	12244051	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
acts upstream of or within positive regulation of proteolysis	IDA IDA: Inferred from direct assay	12244051	GOA

Cellular Component GO Annotation	Evidence	参考文献	由来
located in mitochondrial matrix	IDA IDA: Inferred from direct assay	27184847	GOA
located in nucleus	IDA IDA: Inferred from direct assay	12244051	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AURKAIP1 Protein Structure

DUF1713

0
100
199 a.a.

Protein Preferred Names	Protein Names
aurora kinase A-interacting protein	28S ribosomal protein S38, mitochondrial

AURKAIP1 Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	AURKAIP1	Q9NWT8	FAM9B	Homo sapiens	Q8IZU0	Y2H Prey Pooling	25416956
Intra	AURKAIP1	Q9NWT8	FAM9B	Homo sapiens	Q8IZU0	Validated Y2H	25416956
Intra	AURKAIP1	Q9NWT8	AURKA	Homo sapiens	O14965	Anti Bait CoIP	12244051
Intra	AURKAIP1	Q9NWT8	AURKA	Homo sapiens	O14965	Anti Tag CoIP	12244051

Cross: Cross-species interaction Intra: Intraspecies interaction

Diseases	Alias
Hermansky-Pudlak Syndrome 3	HPS3 Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Delta Storage Pool Disease Hermansky-Pudlak Syndrome, Type 3 Platelet Storage Pool Deficiency Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS01269	AURKAIP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Canis familiaris	AURKAIP1	VGNC	VGNC:56004
Macaca mulatta	AURKAIP1	VGNC	VGNC:106321
Bos taurus	AURKAIP1	VGNC	VGNC:26350
Mus musculus	AURKAIP1	MGD	MGI:1913327
Felis catus	AURKAIP1	VGNC	VGNC:60043
Others	AURKAIP1	NCBI