CASKIN1 - CASK interacting protein 1 Gene

Also Known as ANKS5A

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 57524

About CASKIN1

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,177,180-2,196,605 (from NCBI)

This gene has 3 transcripts (splice variants), 254 orthologues and 1 paralogue. Broad expression in brain (RPKM 9.2), colon (RPKM 2.0) and 23 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]

CASKIN1 Products (1)

mRNA Protein Name
NM_020764.4 NP_065815.1 caskin-1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables identical protein binding IPI
IPI: Inferred from physical interaction
21763699 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21763699 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CASKIN1 Protein Structure

Ank_5

Ank_5: Ankyrin repeats (many copies) (39 - 89)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (99 - 170)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (173 - 251)

SH3_2

SH3_2: Variant SH3 domain (286 - 341)

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (472 - 532)

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (547 - 602)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1431 a.a.
Protein Preferred Names Protein Names

caskin-1

CASKIN1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
CASKIN1 Q8WXD9 CASK Homo sapiens O14936
GMS
21763699
Intra
CASKIN1 Q8WXD9 CASK Homo sapiens O14936
BN-PAGE
21763699
Intra
CASKIN1 Q8WXD9 CASK Homo sapiens O14936
SPR
21763699
Intra
CASKIN1 Q8WXD9 CASK Homo sapiens O14936-2
TEM
22153505
Intra
CASKIN1 Q8WXD9 CASK Homo sapiens O14936-2
Solution Sedimentation
22153505
Intra
CASKIN1 Q8WXD9 CASKIN1 Homo sapiens Q8WXD9
SPR
22153505
Intra
CASKIN1 Q8WXD9 CASKIN1 Homo sapiens Q8WXD9
TEM
22153505
Intra
CASKIN1 Q8WXD9 CASKIN1 Homo sapiens Q8WXD9
X-Ray Diffraction
22153505
Intra
CASKIN1 Q8WXD9 CASKIN1 Homo sapiens Q8WXD9
BN-PAGE
21763699
Intra
CASKIN1 Q8WXD9 CASKIN1 Homo sapiens Q8WXD9
GMS
22153505
Intra
CASKIN1 Q8WXD9 CASKIN1 Homo sapiens Q8WXD9
LM
22153505
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Syndromic X-Linked Intellectual Disability Najm Type

  • Mental Retardation And Microcephaly With Pontine And Cerebellar Hypoplasia

  • Micpch

  • X-Linked Intellectual Disability-Microcephaly-Pontocerebellar Hypoplasia Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS01939 CASKIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus CASKIN1 RGD RGD:620191
Macaca mulatta CASKIN1 VGNC VGNC:70593
Felis catus CASKIN1 VGNC VGNC:82359
Bos taurus CASKIN1 VGNC VGNC:26777
Canis familiaris CASKIN1 VGNC VGNC:38730
Mus musculus CASKIN1 MGD MGI:2442952
Others CASKIN1 NCBI