CASKIN1 - CASK interacting protein 1 Gene

Homo sapiens

Also known as ANKS5A

Gene ID: 57524 | Gene type: protein coding

About CASKIN1

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,177,180-2,196,605 (from NCBI)

This gene has 3 transcripts (splice variants), 254 orthologues and 1 paralogue. Broad expression in brain (RPKM 9.2), colon (RPKM 2.0) and 23 other tissues.

Summary

Enables identical protein binding activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]

CASKIN1 Products(1)

mRNA	Protein	Name
NM_020764.4	NP_065815.1	caskin-1

CASKIN1 Protein Structure

Ank_5

Ank_2

SH3_2

SAM_1

0
300
600
900
1200
1431 a.a.

Protein Preferred Names

Protein Names

caskin-1

Related Diseases

Diseases

Alias

Syndromic X-Linked Intellectual Disability Najm Type

Mental Retardation And Microcephaly With Pontine And Cerebellar Hypoplasia	Micpch
X-Linked Intellectual Disability-Microcephaly-Pontocerebellar Hypoplasia Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-115719	CASK-IN-1	Inhibitor	/	Unkown
HY-RS01939	CASKIN1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CASKIN1	RGD	RGD:620191
Macaca mulatta	CASKIN1	VGNC	VGNC:70593
Felis catus	CASKIN1	VGNC	VGNC:82359
Bos taurus	CASKIN1	VGNC	VGNC:26777
Canis familiaris	CASKIN1	VGNC	VGNC:38730
Mus musculus	CASKIN1	MGD	MGI:2442952

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