PROTAC EZH2 Degrader-11
PROTAC EZH2 Degrader-11 (compound 2) is a EZH2-targeting PROTAC protein degrader. PROTAC EZH2 Degrader-11 reduces tumor size and viability in 3D spheroid models. PROTAC EZH2 Degrader-11 can be used for the research of cancer.
(Pink: EZH2 ligand (HY-13470); Blue: Cereblon ligand (HY-103596); Black: linker).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2653338-61-3
- 分子式: C49H56N8O7
- 分子量:869.02
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2653338-61-3
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分子量 869.02
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分子式 C49H56N8O7
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SMILES
CC[C@H](C)N1C=C(C)C2=C(C(NCC3=C(C)C=C(C)NC3=O)=O)C=C(C4=CN=C(N5CCN(CCCCCOC6=C7C(N(C8CCC(NC8=O)=O)C(C7=CC=C6)=O)=O)CC5)C=C4)C=C21
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)