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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
174 Results for "
DPP-4
" in MedChemExpress (MCE) Product Catalog:
Products (174)
174 Results for "DPP-4" in MCE Product Catalog:
Target:
研究分野:
N-Boc-Sitagliptin is an intermediate in the synthesis of the dipeptidyl peptidase 4 (DPP-4) inhibitor Sitagliptin (HY-13749).
製品番号: HY-W003592A
CAS 番号: 42538-31-8
Target:
研究分野:
L-Orinithine lactam hydrochloride is a synthetic intermediate. L-Orinithine lactam (hydrochloride) can be used in the synthesis of dipeptidyl peptidase 4 (DPP-4) inhibitors, as well as signaling peptides .
製品番号: HY-13749C
CAS 番号: 823817-58-9
別名: (S)-MK-0431 phosphate
Target:
研究分野:
(S)-Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts .
製品番号: HY-RS03964
Target:
研究分野:
Dpp4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dpp4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-155027
DPP-4-IN-8 (compound 27) is a potent and selective DPP4 (dipeptidyl peptidase 4) inhibitor, with a Ki of 0.96 μM. DPP-4-IN-8 blocks the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells. DPP-4-IN-8 also dose-dependently suppresses the expression levels of the chemokines tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) .
製品番号: HY-Z1764
CAS 番号: 486460-31-5
別名: Sitagliptin impurity 3
Target:
研究分野:
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC50 of 27 nM. DPP-4-IN-18 can effectively prevent DPP-4 from degrading glucagon-like peptide 1 (GLP-1), thereby increasing the level of active GLP-1. DPP-4-IN-18 can be used for the research of type 2 diabetes .
製品番号: HY-RS03963
Target:
研究分野:
DPP4 Human Pre-designed siRNA Set A contains three designed siRNAs for DPP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS03965
Target:
研究分野:
Dpp4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dpp4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-A0023AR
CAS 番号: 850649-61-5
別名: SYR-322 free base (Standard)
Alogliptin (Standard) is the analytical standard of Alogliptin. This product is intended for research and analytical applications. Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with an IC50 of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin can be used for the research of type 2 diabetes .
製品番号: HY-146455
CAS 番号: 2402735-14-0
DPP-4-IN-3 (Compound 5a) is a potent dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 0.75 nM. DPP-4-IN-3 shows excellent antioxidant and insulinotropic activity .
製品番号: HY-146469
CAS 番号: 2010927-65-6
Target:
研究分野:
DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 μM for DPP-IV and an EC50 of 0.95 μM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research . DPP-4/GPR119 modulator 2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
製品番号: HY-157390
CAS 番号: 2906243-39-6
Target:
研究分野:
DPP-4-IN-9 (compound 6l) is a potent inhibitor of dipeptidyl peptidase DPP-4 (IC50: 8.22 nM). DPP-4-IN-9 has antihyperglycemic activity .
製品番号: HY-14806R
CAS 番号: 760937-92-6
別名: MP-513 (Standard)
研究分野:
Teneligliptin (Standard) is the analytical standard of Teneligliptin. This product is intended for research and analytical applications. Teneligliptin (MP-513) is a potent, orally available, competitive, and long-lasting DPP-4 inhibitor. Teneligliptin competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM .
製品番号: HY-14892B
CAS 番号: 1375415-82-9
別名: LC15-0444 tartrate hydrate
Target:
研究分野:
Gemigliptin (LC15-0444 ) tartrate hydrate is a selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate hydrate exhibits potent anti-glycation properties. Gemigliptin tartrate hydrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications .
製品番号: HY-174832
Target:
研究分野:
DPP-4-IN-16 (Compound 92) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor (IC50=0.8 nM). DPP-4-IN-16 inhibits DPP-4-mediated degradation of incretins (e.g., GLP-1 and GIP) to promote insulin secretion and reduce blood glucose. DPP-4-IN-16 is promising for research of type 2 diabetes .
製品番号: HY-10284R
CAS 番号: 668270-12-0
別名: BI 1356 (Standard)
Linagliptin (Standard) is the analytical standard of Linagliptin. This product is intended for research and analytical applications. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
製品番号: HY-110051
CAS 番号: 866396-70-5
DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that can reduce DPP4 expression .
製品番号: HY-170657
Target:
研究分野:
DPP-4-IN-14 (compound 30) is a DPP-4 inhibitor, with an IC50 of 12.82 nM .
製品番号: HY-169110
Target:
研究分野:
DPP-4-IN-12 (compound 46) is a potent DPP-4 inhibitor with IC50 value of 2 nM. DPP-4-IN-12 can be used in the study of type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
