1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. KRAS G12C inhibitor 32

KRAS G12C inhibitor 32, an eight membered heterocyclic compound containing N, is a potent KRAS G12C inhibitor.

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KRAS G12C inhibitor 32

KRAS G12C inhibitor 32 Estructura química

No. CAS : 2756739-00-9

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Descripciòn

KRAS G12C inhibitor 32, an eight membered heterocyclic compound containing N, is a potent KRAS G12C inhibitor[1].

IC50 & Target[1]

KRAS (G12C)

 

In Vitro

KRAS G12C inhibitor 32 (compound 6 or 7) inhibits proliferation of NCI-H358IC cell (IC50=0.015 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

635.94

Fòrmula

C29H30Cl3FN6O3

No. CAS
SMILES

C=CC(N1CCN(C2=NC(OC[C@@H]3CCCN3C)=NC4=C5C(C6=C(C(Cl)=CC(Cl)=C6NCCO5)F)=C(Cl)C=C24)CC1)=O

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Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
KRAS G12C inhibitor 32
Cat. No.:
HY-142487
Cantidad:
MCE Japan Authorized Agent: