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Cat. No.: HY-147632

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KRAS G12C inhibitor 51

KRAS G12C inhibitor 51 (example 1) is a KRAS G12C inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2762632-78-8
Formula: C₃₃H₃₅FN₆O₃
Molecular Weight:582.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KRAS G12C inhibitor 51 Chemical Structure

CAS No.: 2762632-78-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

KRAS G12C inhibitor 51 (example 1) is a KRAS G12C inhibitor^[1].

IC₅₀ & Target

KRAS(G12C)

All Ras Isoforms :

Chemical Information

CAS No. 2762632-78-8
Molecular Weight 582.67
Formula C₃₃H₃₅FN₆O₃
SMILES

C=CC(N1CCN([C@H](C1)C)C2=NC(N(C3=NC(C4=C(C=CC=C4O)F)=C(C=C32)C5CC5)C6=C(N=CC=C6C)C(C)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ning Xi, et al. Pyrimidone derivatives and their use in medicine. CN114075195A.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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KRAS G12C inhibitor 51

All Ras Isoforms