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Cat. No.: HY-147636

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KRAS G12C inhibitor 55

KRAS G12C inhibitor 55 (Compound 1) is a KRAS G12C inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2508134-76-5
Formula: C₃₆H₄₀F₃N₇O₂
Molecular Weight:659.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KRAS G12C inhibitor 55 Chemical Structure

CAS No.: 2508134-76-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KRAS G12C inhibitor 55 (Compound 1) is a KRAS G12C inhibitor^[1].

IC₅₀ & Target

KRAS(G12C)

All Ras Isoforms :

In Vitro

KRAS G12C inhibitor 55 (Compound 1) shows inhibition for CALU-1 cells with an IC₅₀ of 2.7 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2508134-76-5
Molecular Weight 659.74
Formula C₃₆H₄₀F₃N₇O₂
SMILES

C=CC(N1CC2(C1)CCN(CC2)C3=NC(C4CCN(CC4)C)=NC5=C(C(C6=C7C=NNC7=CC=C6C)=C(C=C35)C=C)OCC(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hao Wu, et al. Quinazoline compound and pharmaceutical composition thereof. WO2022083616A1.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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KRAS G12C inhibitor 55

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRAS G12C inhibitor 55 Related Classifications

HY-147636 Related Classifications