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Cat. No.: HY-139911

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KRAS G12D inhibitor 7

KRAS G12D inhibitor 7 is an inhibitor of KRAS G12D. KRAS G12D inhibitor 7 can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 2648552-34-3
Formula: C₃₂H₃₈N₈O₃
Molecular Weight:582.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

KRAS G12D inhibitor 7 Chemical Structure

CAS No.: 2648552-34-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KRAS G12D inhibitor 7 is an inhibitor of KRAS G12D. KRAS G12D inhibitor 7 can be used for the research of cancer^[1].

IC₅₀ & Target

KRas G12D

All Ras Isoforms :

In Vitro

KRAS G12D inhibitor 7 (Compound example 114) blocks the activation of the downstream signaling pathway of Ras and exerts anti-tumor activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2648552-34-3
Molecular Weight 582.70
Formula C₃₂H₃₈N₈O₃
SMILES

CN(CCC1)[C@@H]1COC2=NC(N3C[C@@H](N(CC3)C([C@H]4CN4)=O)CC#N)=C5C(CN(C6=CC(O)=CC7=C6C=CC=C7)CC5)=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. PITZEN, Jennifer, et al. COVALENT RAS INHIBITORS AND USES THEREOF. Patent WO2021108683A1. 2022-05-27

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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KRAS G12D inhibitor 7

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRAS G12D inhibitor 7 Related Classifications

HY-139911 Related Classifications