2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. KV1.3-IN-2 hydrochloride

KV1.3-IN-2 hydrochloride is a kv1.3 potassium channel inhibitor without affecting hERG channel activity. KV1.3-IN-2 hydrochloride can be used in research of immune-related diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.

For research use only. We do not sell to patients.

KV1.3-IN-2 hydrochloride

KV1.3-IN-2 hydrochloride Chemical Structure

CAS No. : 3071928-61-2

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Based on 1 publication(s) in Google Scholar

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KV1.3-IN-2 hydrochloride Related Antibodies

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Description

KV1.3-IN-2 hydrochloride is a kv1.3 potassium channel inhibitor without affecting hERG channel activity. KV1.3-IN-2 hydrochloride can be used in research of immune-related diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus[1].

IC50 & Target[1]

Kv1.3

 

In Vitro

KV1.3-IN-2 (Compound I) hydrochloride inhibits the activity of the Kv1.3 potassium channel without blocking the hERG channel, resulting in reduced cardiotoxicity risk, enhanced ion channel selectivity, improved pharmacokinetic properties, and increased solubility[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

KV1.3-IN-2 hydrochloride Related Antibodies
Molecular Weight

379.28

Formula

C16H24Cl2N2O4
CAS No.
Appearance

Solid

SMILES

OC1=CC(C)=C(Cl)C=C1[C@H](N)C2CCN(C([C@@H](CO)O)=O)CC2.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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KV1.3-IN-2 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KV1.3-IN-23071928-61-2Potassium ChannelKcsAPsoriasisRheumatoid arthritisSystemic lupus erythematosusInhibitorinhibitorinhibit

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