L-Proline tert-butyl ester hydrochloride
Based on 1 Customer Validation
L-Proline tert-butyl ester hydrochloride (tert-Butyl L-prolinate hydrochloride) is a proline derivative in the form of tert-butyl ester hydrochloride, which is applicable to research related to protease inhibitors.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 5497-76-7
- Formula: C9H18ClNO2
- Molecular Weight:207.70
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
L-Proline tert-butyl ester hydrochloride (compound 014-1) is a proline derivative in the form of tert-butyl ester hydrochloride, which serves as an intermediate in the synthesis of compound 013B. Compound 013B significantly inhibits the activity of KRASG12D and also exerts a significant inhibitory effect on phosphorylated ERK in GP2D cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 5497-76-7
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Appearance Solid
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Molecular Weight 207.70
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Formula C9H18ClNO2
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Color White to off-white
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SMILES
CC(C)(OC([C@]1([H])CCCN1)=O)C.Cl
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Synonyms
tert-Butyl L-prolinate hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (481.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8146 mL | 24.0732 mL | 48.1464 mL | 120.3659 mL |
| 5 mM | 0.9629 mL | 4.8146 mL | 9.6293 mL | 24.0732 mL | |
| 10 mM | 0.4815 mL | 2.4073 mL | 4.8146 mL | 12.0366 mL | |
| 15 mM | 0.3210 mL | 1.6049 mL | 3.2098 mL | 8.0244 mL | |
| 20 mM | 0.2407 mL | 1.2037 mL | 2.4073 mL | 6.0183 mL | |
| 25 mM | 0.1926 mL | 0.9629 mL | 1.9259 mL | 4.8146 mL | |
| 30 mM | 0.1605 mL | 0.8024 mL | 1.6049 mL | 4.0122 mL | |
| 40 mM | 0.1204 mL | 0.6018 mL | 1.2037 mL | 3.0091 mL | |
| 50 mM | 0.0963 mL | 0.4815 mL | 0.9629 mL | 2.4073 mL | |
| 60 mM | 0.0802 mL | 0.4012 mL | 0.8024 mL | 2.0061 mL | |
| 80 mM | 0.0602 mL | 0.3009 mL | 0.6018 mL | 1.5046 mL | |
| 100 mM | 0.0481 mL | 0.2407 mL | 0.4815 mL | 1.2037 mL |
L-Proline tert-butyl ester hydrochloride Related Classifications
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