2. GPCR/G Protein
  3. Adenosine Receptor
  4. LAS38096

LAS38096 is a potent, selective, and efficacious A2B Adenosine Receptor antagonist, with a Ki of 17 nM.

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LAS38096

LAS38096 Estructura química

No. CAS : 851371-22-7

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1 mg Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg   Obtener un presupuesto  
10 mg   Obtener un presupuesto  
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LAS38096 Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Adenosine Receptor:

Ver todas las isoformas
Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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Descripciòn

LAS38096 is a potent, selective, and efficacious A2B Adenosine Receptor antagonist, with a Ki of 17 nM[1].
IC50 & Target[1].

A2B

17 nM (Ki)

A1

>1000 nM (Ki)

A2A

>2500 nM (Ki)

A3

>1000 nM (Ki)

Cellular Effect
Cell Line Type Value Description References
CHO IC50
349 nM
Compound: 5, LAS38096
Activity at mouse A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced intracellular cAMP levels by ELISA
Activity at mouse A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced intracellular cAMP levels by ELISA
[PMID: 17469811]
HEK293 IC50
321 nM
Compound: 5, LAS38096
Activity at human A2B receptor expressed in HEK293 cells assessed as inhibition of NECA-induced intracellular cAMP levels by ELISA
Activity at human A2B receptor expressed in HEK293 cells assessed as inhibition of NECA-induced intracellular cAMP levels by ELISA
[PMID: 17469811]
Peso molecular

316.32

Fòrmula

C17H12N6O
No. CAS
SMILES

C1(C2=CN=C(NC3=CC=CN=C3)N=C2C4=CC=CO4)=NC=NC=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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LAS38096 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LAS38096851371-22-7LAS 38096LAS-38096Adenosine ReceptorP1 receptorA2BInhibitorinhibitorinhibit

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Nombre del producto:
LAS38096
Cat. No.:
HY-111295
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