Lipid Carboxylic Acid

Lipid Carboxylic Acid (26):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

DSPE-PEG2000-COOH	1445832-74-5	99.95%
DSPE-PEG (2000)-COOH is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530). DSPE-PEG2000-COOH can form micelles for targeted drug delivery.

DSPE-PEG2000 Carboxylic acid sodium	1403744-37-5	98.0%
DSPE-PEG2000 Carboxylic acid sodium is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles.

DSPE-PEG-COOH, MW 2000		99.95%
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.

DSPE-PEG5000-COOH		98.07%
DSPE-PEG5000-COOH is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG5000-COOH can be used in drug delivery research.

16:0 Succinyl PE	186800-61-3	99.34%
16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.

DSPE-succinic acid	248253-94-3	99.72%
DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer.

DSPE-PEG12 carboxy sodium	3091879-93-2
DSPE-PEG12 carboxy sodium is a lipid that consists of a DSPE-PEG12 unit conjugated to a carboxy group. DSPE-PEG12 carboxy sodium can be used to prepare lipid nanoparticles for drug delivery.

DSPE-PEG400 carboxylic acid sodium
DSPE-PEG400 carboxylic acid sodium is a lipid that consists of a DSPE-PEG400 unit conjugated to a carboxy group. DSPE-PEG400 carboxylic acid sodium can be used to prepare lipid nanoparticles for drug delivery.

Pomalidomide-C2-PEG-NHCO-C2-COOH	2376050-06-3
Pomalidomide-C2-PEG-NHCO-C2-COOH is a conjugate of the CRBN ligand (HY-10984) and the linker (E3 Ligase Ligand-Linker Conjugate). Pomalidomide-C2-PEG-NHCO-C2-COOH can be used for synthesizing PROTAC ASK1 degrader dASK1 (HY-174862).

DSPE-PEG3400-COOH
DSPE-PEG3400-COOH is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-COOH can be used in drug delivery research.

DOPE-PEG5000-COOH
DOPE-PEG5000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-COOHcan be used in drug delivery research.

DOPE-PEG3400-COOH
DOPE-PEG3400-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-COOHcan be used in drug delivery research.

DOPE-PEG1000-COOH
DOPE-PEG1000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-COOHcan be used in drug delivery research.

Cholesterol-PEG5000-acid
Cholesterol-PEG5000-acid is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG5000-acid can be used in drug delivery research.

Cholesterol-PEG3400-acid
Cholesterol-PEG3400-acid is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG3400-acid can be used in drug delivery research.

18:1 Dodecanyl PE	474923-47-2
18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.

16:0 Glutaryl PE	474923-45-0
16:0 Glutaryl PE is is a carboxylic acid-functionalized lipid with a three carbon linker to a phosphoethanolamine bound to two palmitic acid tails.

18:1 Succinyl PE	111613-33-3
18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.

DSPE-PEG-Carboxylic acid ammonium	474922-20-8
DSPE-PEG-Carboxylic acid ammonium is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted agents and genes.

DSPE-PEG14-COOH
DSPE-PEG14-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

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