Lithium chloride, 99%
Based on 1 Customer Validation
Lithium chloride, for molecular biology, 99% can be used in the preparation of wash buffers for chromatin immunoprecipitation. Lithium chloride, for molecular biology, 99% is a kind of biological materials or organic compounds that are widely used in life science research.
For research use only. We do not sell to patients.
- Purity: 99.55%
- CAS No.: 7447-41-8
- Formula: LiCl
- Molecular Weight:42.39
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-B0726
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Magnesium sulfate, for cell culture -
HY-Y1878
Copper(Ⅱ) sulfate -
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Anhydrous potassium carbonate, 99.995% metals basis -
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Magnesium sulfate -
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Potassium iodide ,meet Ch.P
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
>3000 μM
Compound: LiCl
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Effective concentration of compound against glycogen synthase kinase-3 in HEK293 cells
Effective concentration of compound against glycogen synthase kinase-3 in HEK293 cells
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[PMID: 15149684] |
| NB-4 | IC50 |
5.32 mM
Compound: LiCl
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Cytotoxicity against human NB-4 cells assessed as reduction in cell viability measured after 24 hrs by CCK-8 assay
Cytotoxicity against human NB-4 cells assessed as reduction in cell viability measured after 24 hrs by CCK-8 assay
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[PMID: 34027661] |
| NB4-DR1 | IC50 |
42.5 mM
Compound: LiCl
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Antiproliferative activity against human NB4-DR1 cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
Antiproliferative activity against human NB4-DR1 cells assessed as reduction in cell viability incubated for 24 hrs by CCK-8 assay
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[PMID: 34027661] |
In Vitro
GSK3β inhibitor
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7447-41-8
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Appearance Solid
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Molecular Weight 42.39
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Formula LiCl
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Color White to off-white
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SMILES
[Li]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (2359.05 mM; Need ultrasonic)
DMSO : 25 mg/mL (589.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (58.98 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (58.98 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 23.5905 mL | 117.9523 mL | 235.9047 mL | 589.7617 mL |
| 5 mM | 4.7181 mL | 23.5905 mL | 47.1809 mL | 117.9523 mL | |
| 10 mM | 2.3590 mL | 11.7952 mL | 23.5905 mL | 58.9762 mL | |
| 15 mM | 1.5727 mL | 7.8635 mL | 15.7270 mL | 39.3174 mL | |
| 20 mM | 1.1795 mL | 5.8976 mL | 11.7952 mL | 29.4881 mL | |
| 25 mM | 0.9436 mL | 4.7181 mL | 9.4362 mL | 23.5905 mL | |
| 30 mM | 0.7863 mL | 3.9317 mL | 7.8635 mL | 19.6587 mL | |
| 40 mM | 0.5898 mL | 2.9488 mL | 5.8976 mL | 14.7440 mL | |
| 50 mM | 0.4718 mL | 2.3590 mL | 4.7181 mL | 11.7952 mL | |
| 60 mM | 0.3932 mL | 1.9659 mL | 3.9317 mL | 9.8294 mL | |
| 80 mM | 0.2949 mL | 1.4744 mL | 2.9488 mL | 7.3720 mL | |
| 100 mM | 0.2359 mL | 1.1795 mL | 2.3590 mL | 5.8976 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Lithium chloride, 99% Related Classifications
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