MAO-A/SERT-IN-1
MAO-A/SERT-IN-1 is an inhibitor of MAO-A/serotonin transporter (SERT). MAO-A/SERT-IN-1 can reduce SERT-mediated reuptake of 5-HT and has neuroprotective effects in cell inhibition models. MAO-A/SERT-IN-1 can improve depressive behavior in zebrafish and mice.
For research use only. We do not sell to patients.
- CAS No.: 3001361-38-9
- Formula: C19H14N2O5
- Molecular Weight:350.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
MAO-A |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L02 | IC50 |
>100 μM
Compound: I7
|
Cytotoxicity against human L02 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human L02 cells incubated for 24 hrs by MTT assay
|
[PMID: 39189331] |
| PC-12 | IC50 |
>10 μM
Compound: I7
|
Cytotoxicity against rat PC-12 cells incubated for 24 hrs by MTT assay
Cytotoxicity against rat PC-12 cells incubated for 24 hrs by MTT assay
|
[PMID: 39189331] |
| SH-SY5Y | IC50 |
>100 μM
Compound: I7
|
Cytotoxicity against human SH-SY5Y cells incubated for 24 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells incubated for 24 hrs by MTT assay
|
[PMID: 39189331] |
Chemical Information
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CAS No. 3001361-38-9
-
Molecular Weight 350.32
-
Formula C19H14N2O5
-
SMILES
O=C(C1=C2C3=NC=CC2=CC(OCCCO[N+]([O-])=O)=C1)C4=C3C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)