1. Neuronal Signaling
  2. Monoamine Oxidase Amyloid-β
  3. MAO-B-IN-10

MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetrated MAO-B (monoamine oxidase-B) inhibitor, with IC50 of 5.3 μM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Aβ (amyloid β) aggregation. MAO-B-IN-10 can be use for Alzheimer’s disease research.

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MAO-B-IN-10

MAO-B-IN-10 화학구조

CAS No. : 2376710-36-8

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제품 설명

MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetrated MAO-B (monoamine oxidase-B) inhibitor, with IC50 of 5.3 μM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Aβ (amyloid β) aggregation. MAO-B-IN-10 can be use for Alzheimer’s disease research[1].

IC50 & Target

MAO-B

5.3 ± 0.22 μM (IC50)

MAO-A

15.9 ± 0.1 μM (IC50)

분자량

394.46

화학식

C23H26N2O4

CAS No.
SMILES

CCN(C(OC1=C(C=C(C=C1)/C=C/C(N2CCC3=C(C2)C=CC=C3)=O)OC)=O)C

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
MAO-B-IN-10
Cat. No.:
HY-146347
수량:
MCE Japan Authorized Agent: