N-Nitrosodibenzylamine-d4
N-Nitrosodibenzylamine-d4 is deuterium labeled N-Nitrosodibenzylamine. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs).
For research use only. We do not sell to patients.
- CAS No.: 20002-23-7
- Formula: C14H10D4N2O
- Molecular Weight:230.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 20002-23-7
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Unlabeled Cas 5336-53-8
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Molecular Weight 230.30
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Formula C14H10D4N2O
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SMILES
[2H]C(C1=CC=CC=C1)([2H])N(N=O)C([2H])([2H])C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Appel KE, et al. DNA damage induced by N-nitrosodibenzylamine and N-nitroso-alpha-acetoxybenzyl-benzylamine in mammalian cell systems and in vivo. Toxicol Lett. 1990 Aug;52(3):269-77. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)